Sercloremine (CGP-4718A), usually as the
hydrochloride
In chemistry, a hydrochloride is an acid salt resulting, or regarded as resulting, from the reaction of hydrochloric acid with an organic base (e.g. an amine). An alternative name is chlorhydrate, which comes from French. An archaic alternati ...
salt
In common usage, salt is a mineral composed primarily of sodium chloride (NaCl). When used in food, especially in granulated form, it is more formally called table salt. In the form of a natural crystalline mineral, salt is also known as r ...
, is a
drug
A drug is any chemical substance other than a nutrient or an essential dietary ingredient, which, when administered to a living organism, produces a biological effect. Consumption of drugs can be via insufflation (medicine), inhalation, drug i ...
which was developed in the 1980s and was formerly under investigation as an
antidepressant
Antidepressants are a class of medications used to treat major depressive disorder, anxiety disorders, chronic pain, and addiction.
Common side effects of antidepressants include Xerostomia, dry mouth, weight gain, dizziness, headaches, akathi ...
, but was never marketed.
It acts as a selective,
reversible inhibitor of monoamine oxidase A
Reversibility can refer to:
* Time reversibility, a property of some mathematical or physical processes and systems for which time-reversed dynamics are well defined
:* Reversible diffusion, an example of a reversible stochastic process
* Reversib ...
(RIMA) and
serotonin reuptake inhibitor
A serotonin reuptake inhibitor (SRI) is a type of drug which acts as a reuptake inhibitor of the neurotransmitter serotonin (5-hydroxytryptamine, or 5-HT) by blocking the drug action, action of the serotonin transporter (SERT). This in turn lea ...
.
References
Reversible inhibitors of MAO-A
Antidepressants
Benzofurans
Piperidines
Chloroarenes
Serotonin reuptake inhibitors
Monoamine oxidase inhibitors
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