Semuloparin (
INN,
USAN) is an experimental
antithrombotic being developed by
Sanofi-Aventis and belongs to the group of
low molecular weight heparins (LMWH). It has completed Phase III
clinical trials for the prevention of
thromboembolism following various kinds of surgery such as
hip replacement, as well as for patients undergoing chemotherapy.
Like
bemiparin
Bemiparin (trade names Ivor and Zibor, among others) is an antithrombotic and belongs to the group of low molecular weight heparins (LMWH).
Medical uses
Bemiparin is used for the prevention of thromboembolism after surgery, and to prevent blood ...
, semuloparin is classified as an ultra-LMWH because of its low
molecular mass of 2000–3000 g/mol on average. (
Enoxaparin
Enoxaparin sodium, sold under the brand name Lovenox among others, is an anticoagulant medication (blood thinner). It is used to treat and prevent deep vein thrombosis (DVT) and pulmonary embolism (PE) including during pregnancy and following c ...
has 4500 g/mol) These heparins have lower anti-
thrombin activity than classical LMWHs and act mainly on
factor Xa, reducing the risk of bleeding.
Statement On A Nonproprietary Name Adopted By The Usan Council: Semuloparin Sodium
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References
Heparins
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