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Sedoheptulose or pseudoheptulose or D-''altro''-heptulose is a ketoheptose—a
monosaccharide Monosaccharides (from Greek '' monos'': single, '' sacchar'': sugar), also called simple sugars, are the simplest forms of sugar and the most basic units (monomers) from which all carbohydrates are built. Chemically, monosaccharides are polyhy ...
with seven
carbon Carbon () is a chemical element; it has chemical symbol, symbol C and atomic number 6. It is nonmetallic and tetravalence, tetravalent—meaning that its atoms are able to form up to four covalent bonds due to its valence shell exhibiting 4 ...
atoms and a
ketone In organic chemistry, a ketone is an organic compound with the structure , where R and R' can be a variety of carbon-containing substituents. Ketones contain a carbonyl group (a carbon-oxygen double bond C=O). The simplest ketone is acetone ( ...
functional group In organic chemistry, a functional group is any substituent or moiety (chemistry), moiety in a molecule that causes the molecule's characteristic chemical reactions. The same functional group will undergo the same or similar chemical reactions r ...
. It is one of the few heptoses found in nature, and is found in various fruits and vegetables ranging from carrots and leeks to figs, mangos and avocados. It is an intermediate in respiratory and photosynthetic pathways and plays a vital role in the non-oxidative branch of the
pentose phosphate pathway The pentose phosphate pathway (also called the phosphogluconate pathway and the hexose monophosphate shunt or HMP shunt) is a metabolic pathway parallel to glycolysis. It generates NADPH and pentoses (five-carbon sugars) as well as ribose 5-ph ...
. Studies have shown that 7-O-galloyl-D-sedoheptulose, a chemical extracted from
dogwood ''Cornus'' is a genus of about 30–60 species of woody plants in the family Cornaceae, commonly known as dogwoods or cornels, which can generally be distinguished by their blossoms, berries, and distinctive bark. Most are deciduous ...
fruit, is able to reduce pro-inflammatory markers ''
in vivo Studies that are ''in vivo'' (Latin for "within the living"; often not italicized in English) are those in which the effects of various biological entities are tested on whole, living organisms or cells, usually animals, including humans, an ...
'' such as interleukin-6 (IL-6) and
C-reactive protein C-reactive protein (CRP) is an annular (ring-shaped) pentameric protein found in blood plasma, whose circulating concentrations rise in response to inflammation. It is an acute-phase protein of hepatic origin that increases following interleukin ...
and thus might be able reduce low-level inflammation in humans. While this compound contains a sedoheptulose moiety, sedoheptulose itself has not been shown to possess the same properties.


See also

* Sedoheptulose 7-phosphate


References

{{Carbohydrates Ketoheptoses