Sebaceous hyperplasia is a disorder of the
sebaceous gland
A sebaceous gland is a microscopic exocrine gland in the skin that opens into a hair follicle to secrete an oily or waxy matter, called sebum, which lubricates the hair and skin of mammals. In humans, sebaceous glands occur in the greatest numb ...
s in which they become enlarged, producing flesh-colored or yellowish, shiny, often umbilicated bumps on the face.
Newly formed nodules often swell with sweating (which is pathognomonic for the condition), but this diminishes over time.
Sebaceous gland
A sebaceous gland is a microscopic exocrine gland in the skin that opens into a hair follicle to secrete an oily or waxy matter, called sebum, which lubricates the hair and skin of mammals. In humans, sebaceous glands occur in the greatest numb ...
s are glands located within the
skin
Skin is the layer of usually soft, flexible outer tissue covering the body of a vertebrate animal, with three main functions: protection, regulation, and sensation.
Other cuticle, animal coverings, such as the arthropod exoskeleton, have diffe ...
and are responsible for secreting an oily substance named
sebum
A sebaceous gland is a microscopic exocrine gland in the skin that opens into a hair follicle to secrete an oily or waxy matter, called sebum, which lubricates the hair and skin of mammals. In humans, sebaceous glands occur in the greatest nu ...
. They are commonly associated with
hair follicle
The hair follicle is an organ found in mammalian skin. It resides in the dermal layer of the skin and is made up of 20 different cell types, each with distinct functions. The hair follicle regulates hair growth via a complex interaction betwe ...
s but they can be found in hairless regions of the skin as well. Their secretion lubricates the skin, protecting it from drying out or becoming irritated.
Sebaceous hyperplasia generally affects newborns as well as middle-aged to elderly adults. The symptoms of this condition are 1–5 mm
papule
A papule is a small, well-defined bump in the skin. It may have a rounded, pointed or flat top, and may have a dip. It can appear with a stalk, be thread-like or look warty. It can be soft or firm and its surface may be rough or smooth. Some ha ...
s on the skin, mainly on the forehead, nose and cheeks, and seborrheic facial skin. The papules may be
cauliflower
Cauliflower is one of several vegetables in the species '' Brassica oleracea'' in the genus ''Brassica'', which is in the Brassicaceae (or mustard) family. It is an annual plant that reproduces by seed. Typically, only the head is eaten – t ...
-shaped. In infants,
acne
Acne, also known as ''acne vulgaris'', is a long-term skin condition that occurs when dead skin cells and oil from the skin clog hair follicles. Typical features of the condition include blackheads or whiteheads, pimples, oily skin, and ...
is sometimes associated with sebaceous hyperplasia.
File:Photography of sebaceous hyperplasia.jpg, Photography of sebaceous hyperplasia, showing a group of papules, in this case on the chest with linear distribution pattern.
File:Dermoscopy of sebaceous hyperplasia.jpg, Dermoscopy of sebaceous hyperplasia. Note the aggregation of yellowish-white clods with linear vessels between or above the clods.
File:High dynamic range dermoscopy of sebaceous hyperplasia.jpg, Dermoscopy of sebaceous hyperplasia with digital high dynamic range
High dynamic range (HDR) is a dynamic range higher than usual, synonyms are wide dynamic range, extended dynamic range, expanded dynamic range.
The term is often used in discussing the dynamic range of various signals such as images, videos, ...
. Note the multi-lobulated clods with central openings.
File:Histopathology of sebaceous hyperplasia.jpg, H&E staining of biopsied lesion of sebaceous hyperplasia: Note the multiple, mature sebaceous lobules attached to the central dilated duct in the upper dermis.
File:Malignant Melanoma right temple medial adjacent sebaceous hyperplasia right temple lateral.jpg, Sebaceous hyperplasia, lateral right temple marked for biopsy with adjacent malignant melanoma in situ, evolving, medial right temple
File:Sebaceaous Hyperplasia Chronic folliculits Right Mid Chest.jpg, Sebaceous hyperplasia with surrounding chronic folliculitis, right mid chest
See also
*
Sebaceous adenoma
*
Sebaceous carcinoma
*
Skin lesion
A skin condition, also known as cutaneous condition, is any medical condition that affects the integumentary system—the organ system that encloses the body and includes skin, nails, and related muscle and glands. The major function of thi ...
References
External links
Epidermal nevi, neoplasms, and cysts
{{Epidermal-growth-stub