Scrutinium Physico-Medicum
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''Scrutinium Physico-Medicum Contagiosae Luis, Quae Pestis Dicitur'' (''A Physico-Medical Examination of the Contagious Pestilence Called the Plague'') is a 1658 work by the
Jesuit The Society of Jesus (; abbreviation: S.J. or SJ), also known as the Jesuit Order or the Jesuits ( ; ), is a religious order (Catholic), religious order of clerics regular of pontifical right for men in the Catholic Church headquartered in Rom ...
scholar
Athanasius Kircher Athanasius Kircher (2 May 1602 – 27 November 1680) was a German Society of Jesus, Jesuit scholar and polymath who published around 40 major works of comparative religion, geology, and medicine. Kircher has been compared to fellow Jes ...
, containing his observations and theories about the
bubonic plague Bubonic plague is one of three types of Plague (disease), plague caused by the Bacteria, bacterium ''Yersinia pestis''. One to seven days after exposure to the bacteria, flu-like symptoms develop. These symptoms include fever, headaches, and ...
that struck Rome in the summer of 1656. Kircher was the first person to view infected blood through a
microscope A microscope () is a laboratory equipment, laboratory instrument used to examine objects that are too small to be seen by the naked eye. Microscopy is the science of investigating small objects and structures using a microscope. Microscopic ...
, and his observations are described in the book. The work was printed on the presses of Vitale Mascardi and dedicated to
Pope Alexander VII Pope Alexander VII (; 13 February 159922 May 1667), born Fabio Chigi, was head of the Catholic Church and ruler of the Papal States from 7 April 1655 to his death, in May 1667. He began his career as a vice- papal legate, and he held various d ...
. Kircher attributed the plague to microscopic 'worms' which appeared due to
spontaneous generation Spontaneous generation is a superseded scientific theory that held that living creatures could arise from non-living matter and that such processes were commonplace and regular. It was hypothesized that certain forms, such as fleas, could ...
, and which infected various organisms through the
food chain A food chain is a linear network of links in a food web, often starting with an autotroph (such as grass or algae), also called a producer, and typically ending at an apex predator (such as grizzly bears or killer whales), detritivore (such as ...
process. Already infected plants would infect the animals that ate them, and the infected animals would infect the humans who ate them. Kircher explained his findings through a series of experiments, but
Francesco Redi Francesco Redi (18 February 1626 – 1 March 1697) was an Italians, Italian physician, naturalist, biologist, and poet. He is referred to as the "founder of experimental biology", and as the "father of modern parasitology". He was the first perso ...
later concluded that there was no
reproducibility Reproducibility, closely related to replicability and repeatability, is a major principle underpinning the scientific method. For the findings of a study to be reproducible means that results obtained by an experiment or an observational study or ...
in these experiments. Redi had attempted to reproduce the experiments which Kircher described, and noted that there was no actual evidence for spontaneous generation in the results. On the other hand, Kircher popularized the idea "that contagion was the method of disease transmission". Kircher's work was discussed by the
Royal Society The Royal Society, formally The Royal Society of London for Improving Natural Knowledge, is a learned society and the United Kingdom's national academy of sciences. The society fulfils a number of roles: promoting science and its benefits, re ...
, and the concept of contagion was soon adopted by several English thinkers.


Background

The plague outbreak in Rome in 1656 killed around 15,000 people in four months. During this period Kircher undertook experiments to try and understand the disease better although there is no evidence that he was directly involved in the medical treatment of the sick. Kircher's previous work, ''
Itinerarium exstaticum ''Itinerarium exstaticum quo mundi opificium'' is a 1656 work by the Jesuit scholar Athanasius Kircher. It is an imaginary dialogue in which an Angels in Christianity, angel named Cosmiel takes the narrator, Theodidactus ('taught by God'), on a j ...
'' had caused trouble with the Jesuit censors and stirred up controversy. Writing about the plague gave him an opportunity to compliment the new pope, Alexander VII, and move attention away from a work that had caused him difficulties. The Jesuit Order had a long-established practice of not writing about medical topics. For this reason, the Jesuit censors who reviewed the book - François Duneau, François le Roy and Celidonio Arvizio - originally refused to authorise it for publication. Eventually, after the opinions of a number of medical authorities had been sought, Superior General
Goschwin Nickel Goswin Nickel (1582 – 31 July 1664) was a German Jesuit priest and the tenth Superior-General of the Society of Jesus. Goswin was born in , North-Westphalia (Germany). He studied in Paderborn and Mainz (1611–1615), where he was promoted p ...
permitted its printing. The published work included testimonials from the distinguished medical scholars Ioannes Benedictus Sinibaldus, Paulus Zachias and Hieronymous Bardi.


Kircher's theories

Kircher summarised three possible explanations for the plague. The first was the hermetic approaches of
Paracelsus Paracelsus (; ; 1493 – 24 September 1541), born Theophrastus von Hohenheim (full name Philippus Aureolus Theophrastus Bombastus von Hohenheim), was a Swiss physician, alchemist, lay theologian, and philosopher of the German Renaissance. H ...
and
Cornelius Agrippa Heinrich Cornelius Agrippa von Nettesheim (; ; 14 September 1486 – 18 February 1535) was a German Renaissance polymath, physician, legal scholar, soldier, knight, theologian, and occult writer. Agrippa's ''Three Books of Occult Philosophy'' pub ...
, the second was the moral explanation for disease, and the third was medical. Kircher agreed that God did send tribulations to afflict mankind, but was most interested in medical research. In ''Scrutinium Physico-Medicum'' Kircher discussed
spontaneous generation Spontaneous generation is a superseded scientific theory that held that living creatures could arise from non-living matter and that such processes were commonplace and regular. It was hypothesized that certain forms, such as fleas, could ...
as the source of the 'worms' which caused the plague, describing experiments he did with rotting meat and with a mixture of soil and water, which produced microscopic creatures. His conclusion was that "plague in general is a living thing" and that it was transmitted by contact from one person to another. Kircher theorised that when the ground was opened by caves and fissures, myriads of tiny creatures escaped that carried putrefaction and infected first plants, then the animals that ate them, and eventually, people. Once these creatures infected the human body, they drove out its natural heat. Once the body was chilled, the
four humours Humorism, the humoral theory, or humoralism, was a system of medicine detailing a supposed makeup and workings of the human body, adopted by Ancient Greek and Roman physicians and philosophers. Humorism began to fall out of favor in the 17th ce ...
were overwhelmed with putrefaction, and the victim began spreading disease in their breath. Kircher recommended the wearing of a dead toad around the neck as a prophylactic against the plague, because he maintained that toads were a scientifically proven magnet attracting the unpleasant vapours that spread the disease.


Significance and Reception

Kircher was the first person to view infected blood through a
microscope A microscope () is a laboratory equipment, laboratory instrument used to examine objects that are too small to be seen by the naked eye. Microscopy is the science of investigating small objects and structures using a microscope. Microscopic ...
(which he called a 'smicroscopus'). Reporting that “the putrid blood of those affected by fevers... sso crowded with worms as to well nigh dumbfound me” he concluded that “Plague is in general a living thing”. It is not clear exactly what Kircher saw through his microscope, but it was certainly not the plague bacillus, which was not discovered until 1894. There were critics of Kircher's ideas, such as Flaminius Gaston, who wrote that Kircher's ideas were such that few people of sound mind embraced them.
Francesco Redi Francesco Redi (18 February 1626 – 1 March 1697) was an Italians, Italian physician, naturalist, biologist, and poet. He is referred to as the "founder of experimental biology", and as the "father of modern parasitology". He was the first perso ...
, a member of the
Accademia del Cimento The Accademia del Cimento (Academy of Experiment), an early scientific society, was founded in Florence in 1657 by students of Galileo, Giovanni Alfonso Borelli and Vincenzo Viviani and ceased to exist about a decade later. The foundation of Acade ...
, published ''Esperienze Intorno alla Generazione degl'Insetti'' (''Experiments on the Generation of Insects'') in 1668. In this work he attempted to reproduce the experiments Kircher claimed to have undertaken in ''Scrutinium physico-medicum'' and found some to be unrepeatable - indeed, Redi questioned whether Kircher had ever even done them himself. Sprinking basil water on powdered scorpion did not generate baby scorpions as Kircher claimed, and he doubted that Kircher had ever successfully generated frogs by mixing ditch dust with water. Nevertheless, Kircher's ideas were taken up by Christian Lange (1619–62), a Leipzig professor, who republished his book with his own preface. A school of medical thinking grew up around Lange and is work in Germany and elsewhere, convinced that contagion was the method of disease transmission as Kircher had argued. Kircher's work was discussed by the
Royal Society The Royal Society, formally The Royal Society of London for Improving Natural Knowledge, is a learned society and the United Kingdom's national academy of sciences. The society fulfils a number of roles: promoting science and its benefits, re ...
, and English thinkers persuaded by his views included
Frederick Slare Frederick Slare or Slear (1647?–1727) was an English physician and chemist, a follower of Robert Boyle and Thomas Sydenham. Early life Born in Old, Northamptonshire, Slare was the son of Frederick Schloer, the German rector there, and Anna, da ...
, Sir Charles Ent and
Walter Charleton Walter Charleton (2 February 1619 – 24 April 1707) was a natural philosopher and English writer. According to Jon Parkin, he was "the main conduit for the transmission of Epicurean ideas to England".Jon Parkin, ''Science, Religion and Politi ...
. ''Scrutinium Physico-Medicum'' also influenced the thinking of
Leibniz Gottfried Wilhelm Leibniz (or Leibnitz; – 14 November 1716) was a German polymath active as a mathematician, philosopher, scientist and diplomat who is credited, alongside Sir Isaac Newton, with the creation of calculus in addition to many ...
, who believed in contagion theory.


Later editions

Later editions of the work were published in Leipzig by Johannes Baverus in 1659, 1671 and 1674. A Dutch translation was published in Amsterdam by Johannes van Waesbergen in 1669, and a German translation by J.C. Brandan in Augsburg in 1680. The Waesbergern translation carried a frontispiece depicting a woman covered in
bubo A bubo (Greek βουβών, ''boubṓn'', 'groin') is adenitis or inflammation of the lymph nodes and is an example of reactive infectious lymphadenopathy. Classification Buboes are a symptom of bubonic plague and occur as painful swellings in ...
es. Above her hangs a portrait of Kircher. The wolf next to her may be a reference to the
Romulus and Remus In Roman mythology, Romulus and (, ) are twins in mythology, twin brothers whose story tells of the events that led to the Founding of Rome, founding of the History of Rome, city of Rome and the Roman Kingdom by Romulus, following his frat ...
myth, symbolising Rome. She is stepping on a toad, mentioned in the book both as the product of spontaneous generation and as a protective against the plague.


External links


digital copy of ''Scrutinium physico-medicum''


References

{{reflist 1658 non-fiction books 1658 in science 17th century in medicine 1659 non-fiction books 1671 non-fiction books 1674 non-fiction books Obsolete scientific theories Athanasius Kircher Plague (disease) Pope Alexander VII Books about viral outbreaks Censored books Cultural depictions of Romulus and Remus