Scott Tanner is a

Canadian Canadians () are people identified with the country of Canada. This connection may be residential, legal, historical or cultural. For most Canadians, many (or all) of these connections exist and are collectively the source of their being ''C ...

scientist, inventor, and entrepreneur. His areas of expertise include

mass spectroscopy Mass spectrometry (MS) is an analytical technique that is used to measure the mass-to-charge ratio of ions. The results are presented as a ''mass spectrum'', a plot of intensity as a function of the mass-to-charge ratio. Mass spectrometry is used ...

, especially

inductively coupled plasma mass spectrometry Inductively coupled plasma mass spectrometry (ICP-MS) is a type of mass spectrometry that uses an inductively coupled plasma to ionize the sample. It atomizes the sample and creates atomic and small polyatomic ions, which are then detected. It i ...

(ICP-MS), and

mass cytometry Mass cytometry is a mass spectrometry technique based on inductively coupled plasma mass spectrometry and time of flight mass spectrometry used for the determination of the properties of cells (cytometry). In this approach, antibodies are Conjugat ...

. Tanner is best known for his work on the fundamentals of inductively coupled plasma mass spectrometry, for the invention of mass cytometry, and co-founding (with

Dmitry Bandura Dmitry Bandura is a Soviet-born Canadian scientist, notable for being one of the co-inventors of the Mass cytometry technology. Bandura co-founded DVS Sciences in 2004 (acquired by Fluidigm in 2014 and then renamed to Standard BioTools in 2022) ...

Vladimir Baranov Vladimir Baranov is a Soviet born Canadian scientist and one of the original co-inventors of Mass cytometry technology... He co-founded DVS Sciences in 2004 (acquired by Fluidigm in 2014 and then renamed to Standard BioTools in 2022) along wit ...

and

Olga Ornatsky Olga Ornatsky is a Soviet born, Canadian scientist. Ornatsky co-founded DVS Sciences in 2004 (acquired by Fluidigm in 2014 and then renamed to Standard BioTools in 2022) along with Dmitry Bandura, Vladimir Baranov and Scott D. Tanner. Biog ...

) DVS Sciences in 2004,(acquired by Fluidigm in 2014 and then renamed to Standard BioTools in 2022) the company that first commercialized the instrument and reagents of mass cytometry.

Early life and education

Tanner was born and raised in

St. Catharines, Ontario St. Catharines is the most populous city in Canada's Niagara Region, the eighth largest urban area in the province of Ontario. As of 2021, St. Catharines has an area of and 136,803 residents. It lies in Southern Ontario, south of Toronto ac ...

Canada. He bought his first chemistry set, from his brother, at age 6. Through his early teenage years, he was provided with laboratory space at

Brock University Brock University is a public university, public research university in St. Catharines, Ontario, Canada. It is the only university in Canada in a UNESCO Biosphere Reserve, at the centre of Canada's Niagara Peninsula on the Niagara Escarpment. The ...

, under the guidance of Dr. E.A. Cherniak and Dr. F.P. Koffyberg, where he attempted to replicate

Geiger–Marsden experiments The Rutherford scattering experiments were a landmark series of experiments by which scientists learned that every atom has a nucleus where all of its positive charge and most of its mass is concentrated. They deduced this after measuring how ...

also known as Rutherford's experiment (scattering of alpha particles by gold foil) using various home-built instruments, including cloud chambers. Tanner graduated with a BSc in chemistry from

York University York University (), also known as YorkU or simply YU), is a public university, public research university in Toronto, Ontario, Canada. It is Canada's third-largest university, and it has approximately 53,500 students, 7,000 faculty and staff, ...

in 1976. During his undergraduate years, he became a nationally ranked gymnast. An injury at the Olympic trials ended his competitive gymnastics career, and he took up marathon running during graduate school (best time 2:47:13). He received a Doctor of Philosophy (Chemistry) from York University in 1980, having studied ion-molecule reaction kinetics and flame ion chemistry with Drs. D.K Bohme and J.M. Goodings.

Biography

Tanner joined SCIEX, which later became MDS SCIEX, in 1980 as a research scientist. He became principal scientist in 2000. In his 25 years at SCIEX, Tanner developed and helped to commercialize a string of

mass spectrometry Mass spectrometry (MS) is an analytical technique that is used to measure the mass-to-charge ratio of ions. The results are presented as a ''mass spectrum'', a plot of intensity as a function of the mass-to-charge ratio. Mass spectrometry is used ...

products. Tanner published over 74 peer-reviewed scientific articles, and holds 22 US patents (with corresponding filings in other countries), including 13 patents on Mass

Cytometry Cytometry is the measurement of number and characteristics of cell (biology), cells. Variables that can be measured by cytometric methods include cell size, cell counting, cell count, cell morphology (shape and structure), cell cycle phase, DNA c ...

technology Tanner was a co-founder of DVS Sciences and, as the president and CEO, saw the company through the development and commercial launch of its first products. The products that DVS Sciences brought to the global market were originally developed at the

University of Toronto The University of Toronto (UToronto or U of T) is a public university, public research university whose main campus is located on the grounds that surround Queen's Park (Toronto), Queen's Park in Toronto, Ontario, Canada. It was founded by ...

where Tanner was a professor in the Institute of Biomaterials and Biomedical Engineering and then in chemistry.

Career

* Principal Scientist SCIEX - 1980-2005 * Associate Professor (CLTA) at the University of Toronto, first in the Institute of Biomaterials and Biomedical Engineering (2005–2008) and then in Chemistry 2008–2013. * President DVS Sciences 2004 - 2015
(acquired by

Fluidigm Standard BioTools Inc., previously known as Fluidigm Corp., is an American life science tools company that offers analytical mass cytometry systems for flow cytometry and tissue imaging, along with associated assays and reagents, as well as an a ...

in 2014) * Adjunct Professor at York University in the Department of Chemistry 2015–2018

Volunteer Work

Chair of the Three Churches Heritage Foundation in Mahone Bay - 2020–Present

Books

* 2003 - Plasma Source Mass Spectrometry: Applications and Emerging Technologies * 2001 - Plasma Source Mass Spectrometry: The New Millennium * 1999 - Plasma Source Mass Spectrometry: New Developments and Applications * 1997 - Plasma Source Mass Spectrometry: Developments and Applications

Research

* Detection of TCDD (dioxin) in soil and water, explosives, chemical agents. * Development of the ELAN 6000 ICP-MS * Development of the DRC Collision/reaction cell * Development of

Mass cytometry Mass cytometry is a mass spectrometry technique based on inductively coupled plasma mass spectrometry and time of flight mass spectrometry used for the determination of the properties of cells (cytometry). In this approach, antibodies are Conjugat ...

Awards and honors

* 2024 York U Alumni Award for Outstanding Achievement * 2020 Lifetime Achievement Award in Plasma Spectrochemistry * 2019 HUPO Award (

Human Proteome Organization The Human Proteome Organization (HUPO) is an international consortium of national proteomics research associations, government researchers, academic institutions, and industry partners. The organization was launched in February 2001, and it promotes ...

) * 2014 Fellow of the

American Institute for Medical and Biological Engineering The American Institute for Medical and Biological Engineering (AIMBE) is a non-profit organization founded in 1991, and headquartered in Washington, D.C. It represents 50,000 medical and Biomedical engineering, biomedical engineers, and academic i ...

* 2011

Inventor of the Year Award for Biomedical and Life Sciences * 2011

Thermo Fisher Scientific Thermo Fisher Scientific Inc. is an American life science and clinical research company. It is a global supplier of analytical instruments, clinical development solutions, specialty diagnostics, laboratory, pharmaceutical and biotechnology s ...

Spectroscopy Award * 2004

Elsevier / Spectrochimica Acta Atomic Spectroscopy Award Elsevier ( ) is a Dutch academic publishing company specializing in scientific, technical, and medical content. Its products include journals such as ''The Lancet'', ''Cell'', the ScienceDirect collection of electronic journals, ''Trends'', the ...

for the most important paper published in ''

Spectrochimica Acta Part B ''Spectrochimica Acta Part B: Atomic Spectroscopy'' is a monthly peer-reviewed scientific journal covering spectroscopy. The journal was established in 1939 as ''Spectrochimica Acta''. In 1967, ''Spectrochimica Acta'' was split into two journals, ...

'' in 2002 (Title: Reaction cells and collision cells for ICP-MS: a tutorial review) in co-authorship with

and

* 200
W.A.E. McBryde medal
from the Canadian Chemical Society of the

Chemical Institute of Canada The Chemical Institute of Canada is a Canadian professional umbrella organization for researchers and professionals in the field of chemistry. It was founded in 1921 as the Canadian Institute of Chemistry until it merged with other groups in 1945 ...

* 2001

Manning Innovation Award The Manning Innovation Awards are awarded by the Ernest C. Manning Awards Foundation to recognize and encourage innovation in Canada. By means of a nomination, Canadian resident citizens, who have demonstrated recent innovative talent in developi ...

, Award of Distinction Dr. Scott Tanner, together with Dr. Vladimir Baranov, received the Manning Award of Distinction from the Manning Innovation Awards Foundation for the remarkable invention of the ICP-MS Dynamic Reaction Cell ( Collision/reaction cell). *1999

Pittcon Editors' Awards Pittcon Editors’ Awards honoured the best new products on show at the Pittsburgh Conference on Analytical Chemistry and Applied Spectroscopy, or Pittcon, for 20 years from 1996 having been established by Dr Gordon Wilkinson, managing editor of ' ...

Perkin-Elmer Sciex for their ELAN 6100 DRC (Dynamic Reaction Cell) ICP-MS system. * Fellow of the

Royal Society of Chemistry The Royal Society of Chemistry (RSC) is a learned society and professional association in the United Kingdom with the goal of "advancing the chemistry, chemical sciences". It was formed in 1980 from the amalgamation of the Chemical Society, the ...

(UK) * Fellow of the

(AIMBE)

Publications

Scott has published more than 75 peer-reviewed articles.
The 13 most cited (more than 200 citations each) include: * May 2011 - Single-Cell Mass Cytometry of Differential Immune and Drug Responses Across a Human Hematopoietic Continuum ) * Sept 2010 - Highly Multiparametric Analysis by Mass Cytometry * Aug 2009 - Mass Cytometry: Technique for Real Time Single Cell Multitarget Immunoassay Based on Inductively Coupled Plasma Time-Of-Flight Mass Spectrometry * Sept 2002 - Reaction Cells and Collision Cells for ICP-MS: A Tutorial Review * April 2002 - A Sensitive and Quantitative Element-Tagged Immunoassay with ICPMS Detection * April 2002 - Detection of Ultratrace Phosphorus and Sulfur by Quadrupole ICPMS with Dynamic Reaction Cell * July 2001 - Reaction Chemistry and Collisional Processes in Multipole Devices for Resolving Isobaric Interferences in ICP–MS * Aug 2000 - A Dynamic Reaction Cell for Inductively Coupled Plasma Mass Spectrometry (ICP-DRC-MS). Part III. * Nov 1999 - A Dynamic Reaction Cell for Inductively Coupled Plasma Mass Spectrometry (ICP-DRC-MS). Part II. Reduction of Interferences Produced within the Cell * March 1999 - Theory, Design, and Operation of a Dynamic Reaction Cell for ICP-MS * Jan 1995 - Characterization of Ionization and Matrix Suppression in Inductively Coupled ‘Cold’ Plasma Mass Spectrometry * June 1992 - Space Charge in ICP-MS: Calculation and Implications * July 1988 - Nonspectroscopic Interelement Interferences in Inductively Coupled Plasma Mass Spectrometry A more complete listing of his publications can be found o
Google Scholar

References

External links

Standard BioTools Corporate website (Formerly Fluidigm, Formerly DVS Sciences)
{{DEFAULTSORT:Tanner, Scott Mass spectrometrists Canadian chemists Fellows of the American Institute for Medical and Biological Engineering Fellows of the Royal Society of Chemistry York University alumni Living people Year of birth missing (living people)