Schradan, named after
Gerhard Schrader
Gerhard Schrader (25 February 1903 – 10 April 1990) was a German chemist specializing in the discovery of new insecticides, hoping to make progress in the fight against hunger in the world. Schrader is best known for his accidental discovery of ...
, is an obsolete
organophosphate insecticide
In organic chemistry, organophosphates (also known as phosphate esters, or OPEs) are a class of organophosphorus compounds with the general structure , a central phosphate molecule with alkyl or aromatic substituents. They can be considered ...
. Schradan itself is a weak cholinesterase inhibitor and requires metabolic activation to become active.
See also
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Dimefox
Dimefox was an organophosphate pesticide. In its pure form it is a colourless liquid with a fishy odour. Dimefox was first produced in 1940 by the group of Gerhard Schrader in Germany. It was historically used as a pesticide, but has been deemed ...
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Mipafox
Mipafox is a highly toxic organophosphate insecticide that can cause delayed neurotoxicity and paralysis. It is an irreversible acetylcholinesterase inhibitor that is resistant to oxime reactivators.
Synthesis
Phosphoryl chloride is first reacted ...
References
Acetylcholinesterase inhibitors
Organophosphate insecticides
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