Samuel or Sam Cooper may refer to:
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Samuel Cooper (painter) (1609–1672), English miniature painter
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Samuel Cooper (clergyman) (1725–1783), Congregationalist minister in Boston, Massachusetts
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Samuel Cooper (surgeon) (1780–1848), English surgeon and writer of medical books
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Samuel Cooper (general) (1798–1876), U.S. Army officer and senior Confederate general officer
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Samuel Cooper (serial killer) (born 1977), American serial killer
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Samuel B. Cooper (1850–1918), U.S. Representative from Texas
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Samuel Cooper Thacher (1785–1818), American clergyman and librarian
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Samuel Cooper (volleyball) (born 2001), Canadian volleyball player
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Sam Cooper (baseball) (1897–?), American baseball player
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Sam Cooper (American football) (1909–1998), American football player
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Sam Cooper (journalist), Canadian investigative journalist and best-selling author
Other uses
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Sam Cooper Boulevard, highway in Memphis, Tennessee
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Sam Cooper (''Criminal Minds: Suspect Behavior''), fictional character on television series ''Criminal Minds: Suspect Behavior''
{{disambiguation, hn=Cooper, Samuel