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SCO-spondin is a
protein Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, respon ...
that in humans is encoded by the ''SSPO''
gene In biology, the word gene (from , ; "... Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a b ...
. SCO-spondin is secreted by the
subcommissural organ The subcommissural organ (SCO) is one of the circumventricular organs of the brain. It is a small glandular structure that is located in the posterior region of the third ventricle, near the entrance of the cerebral aqueduct. The name of th ...
, and contributes to commissural axon growth and the formation of
Reissner's fiber Reissner's fiber ''(named after Ernst Reissner)'' is a fibrous aggregation of secreted molecules extending from the subcommissural organ (SCO) through the ventricular system and central canal to the terminal ventricle, a small ventricle-like str ...
, a fibrous aggregation of secreted molecules extending from the subcommissural organ to the end of the spinal cord.


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Further reading

* * * * * * * {{protein-stub Extracellular matrix proteins