Spoo may refer to:
*
Bob Spoo
Robert Allen Spoo (November 2, 1937 – October 15, 2018) was an American college football coach. He served as the head football coach at Eastern Illinois University from 1987 to 2011 (with an interruption in 2006 due to surgery), compiling a reco ...
(1937–2018), an American college football coach
*
Caspar Mathias Spoo
Caspar Mathias Spoo (7 January 1837 – 17 March 1914) was a Luxembourgish industrialist and politician.
Spoo was born in Echternach in 1837. His parents were workers in the earthenware factory, and died early. He joined the civil service from a ...
(1837–1914), a Luxembourgish industrialist and politician
* Spoo, a fictional food in the ''
Babylon 5'' science fiction television series
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