Spea or SPEA may refer to:
*
Spea
''Spea'' is a genus of North American amphibian commonly referred to as the western spadefoot toads. They differ greatly from true toads (those of the family Bufonidae) by having eyes with vertical pupils, no parotoid glands, and relatively smoo ...
, a genus of amphibians
*
SpeA
''Spea'' is a genus of North American amphibian commonly referred to as the western spadefoot toads. They differ greatly from true toads (those of the family Bufonidae) by having eyes with vertical pupils, no parotoid glands, and relatively smoo ...
, an enzyme also known as arginine decarboxylase
* SPEA (company), an Italian tech company
*
School of Public and Environmental Affairs at Indiana University
*
Spea Software AG, a defunct German computer graphics hardware company
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