SNX26
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TC10/CDC42 GTPase-activating protein is an
enzyme An enzyme () is a protein that acts as a biological catalyst by accelerating chemical reactions. The molecules upon which enzymes may act are called substrate (chemistry), substrates, and the enzyme converts the substrates into different mol ...
that in humans is encoded by the ''SNX26''
gene In biology, the word gene has two meanings. The Mendelian gene is a basic unit of heredity. The molecular gene is a sequence of nucleotides in DNA that is transcribed to produce a functional RNA. There are two types of molecular genes: protei ...
. This gene encodes a member of the
sorting nexin Sorting nexins are a large group of proteins that are localized in the cytoplasm and have the potential for membrane association either through their lipid-binding PX domain (a phospholipid-binding Structural motif, motif) or through proteinâ ...
family. Members of this family contain a
phox In automated theorem proving, PhoX is a proof assistant based on higher-order logic which is eXtensible. The user gives PhoX an initial goal and guides it through subgoals and evidence to prove that goal; internally, it constructs natural deduction ...
(PX) domain, which is a
phosphoinositide Phosphatidylinositol or inositol phospholipid is a biomolecule. It was initially called "inosite" when it was discovered by Léon Maquenne and Johann Joseph von Scherer in the late 19th century. It was discovered in bacteria but later also found ...
binding domain, and are involved in intracellular trafficking. The specific function of this protein has not been elucidated. Alternative splice variants have been described but their full length nature has not been determined.


References


Further reading

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