SLC45A1 is a member of the SLC45 family of
solute carriers. Analysis of the protein function in a recombinant yeast expression assay show that it can:
(i) transport a disaccharide, such as glucose and sucrose
(ii) perform secondary active transport in a proton-dependent manner.
It is associated with sugar transport in the brain, and rare mutations in the gene are associated with intellectual disability and epilepsy.
analogous to the effect of mutation of the cerebral glucose transporter
GLUT1
Glucose transporter 1 (or GLUT1), also known as solute carrier family 2, facilitated glucose transporter member 1 (SLC2A1), is a uniporter protein that in humans is encoded by the ''SLC2A1'' gene. GLUT1 facilitates the transport of glucose acro ...
(SLC2A1).
References
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Solute carrier family