SCAN domain-containing protein 1 is a
protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residue (biochemistry), residues. Proteins perform a vast array of functions within organisms, including Enzyme catalysis, catalysing metab ...
that in humans is encoded by the ''SCAND1''
gene
In biology, the word gene has two meanings. The Mendelian gene is a basic unit of heredity. The molecular gene is a sequence of nucleotides in DNA that is transcribed to produce a functional RNA. There are two types of molecular genes: protei ...
.
Function
The SCAN domain is a highly conserved, leucine-rich motif of approximately 60 amino acids originally found within a subfamily of zinc finger proteins. This gene belongs to a family of genes that encode an isolated SCAN domain, but no zinc finger motif. Functional studies have established that the SCAN box is a protein interaction domain that mediates both hetero- and homoprotein associations, and maybe involved in regulation of transcriptional activity. Two transcript variants with different 5' UTRs, but encoding the same protein, have been described for this gene.
Interactions
SCAND1 has been shown to
interact
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with
MZF1
Myeloid zinc finger 1 is a protein that in humans is encoded by the ''MZF1'' gene.
Interactions
MZF1 has been shown to interact with SCAND1.
In 2014, the laboratory of Nathan H. Lents showed that MZF-1 induces the GAPDH
Glyceraldehy ...
.
References
Further reading
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