Acts and projects
* SAFE Act, one of many passed or proposed laws with this name * Strategic Action For Emergencies, a fictional group to counter S.H.I.E.L.D. in Marvel Comics * Synchronized Armed Forces Europe, the concept of synchronising of the European military forcesOrganisations
* SAFE (New Zealand organisation), Save Animals From Exploitation, a New Zealand animal advocacy organisation * SAFE Society of Aviation and Flight Educators, a professional aviation organization * SAFE Stroke Alliance for Europe, a coalition of charities that support stroke survivors * SAFE (Struggle Against Financial Exploitation), a UK Parliamentary Working Group who campaign against financial fraud and deception * Safe Ireland, anti-domestic violence organization, fund-raised for by Hozier' song ''Cherry Wine'' * State Administration of Foreign Exchange (SAFE) an agency of the People's Republic of ChinaScience and technology
* Scaled agile framework (SAFe), a process framework for running Agile software development projects at scale * SAFE (cable system), South Africa Far East cable, an underwater communications cable linking South Africa and Malaysia * Safe affordable fission engine, a series of small experimental nuclear reactors designed by NASA * Survivor Activating Factor Enhancement, a metabolic pathwayInvesting
* Simple agreement for future equity (SAFE), a financing vehicle for startup businesses providing an alternative to a priced equity round or to a convertible noteSee also
* Safe (disambiguation) {{Disambiguation