Ruth Bishop
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Ruth Frances Bishop (12 May 1933 – 12 May 2022)''Who's Who in Australia'', ConnectWeb, 2013. was an Australian
virologist Virology is the scientific study of biological viruses. It is a subfield of microbiology that focuses on their detection, structure, classification and evolution, their methods of infection and exploitation of host cells for reproduction, the ...
, who was a leading member of the team that discovered the human
rotavirus Rotaviruses are the most common cause of diarrhea, diarrhoeal disease among infants and young children. Nearly every child in the world is infected with a rotavirus at least once by the age of five. Immunity (medical), Immunity develops with ...
.


Biography

Bishop was born in
Dandenong, Victoria Dandenong ( ) is a southeastern suburb of Melbourne, Victoria, Australia, about from the Melbourne CBD. It is the council seat of the City of Greater Dandenong local government area, with a recorded population of 30,127 at the . Situated m ...
, and grew up in Frankston where her father was principal of Frankston High School.Precel, Nicole (30 October 2013).
Professor Ruth Bishop wins 2013 CSL Florey Medal
. '' Frankston Standard Leader''.
News Limited News Corp Australia is an Australian media conglomerate and wholly owned subsidiary of News Corp. The group's interests span newspaper and magazine publishing, Internet, market research, DVD and film distribution, and film and television pr ...
. Retrieved 17 October 2015
Bishop obtained a BSc., majoring in
microbiology Microbiology () is the branches of science, scientific study of microorganisms, those being of unicellular organism, unicellular (single-celled), multicellular organism, multicellular (consisting of complex cells), or non-cellular life, acellula ...
, in 1954 followed by a M. Sc. in the same field in 1958 and graduated with a
PhD A Doctor of Philosophy (PhD, DPhil; or ) is a terminal degree that usually denotes the highest level of academic achievement in a given discipline and is awarded following a course of graduate study and original research. The name of the deg ...
in microbiology in 1961. In 1973, Bishop, along with Geoffrey Davidson (
Royal Children's Hospital The Royal Children's Hospital (RCH), colloquially referred to as the Royal Children's, is a major children's hospital in Parkville, Victoria, Parkville, a suburb of Melbourne, Victoria (state), Victoria, Australia. Regarded as one of the great C ...
) and collaborators Ian Holmes and Brian Ruck (
University of Melbourne The University of Melbourne (colloquially known as Melbourne University) is a public university, public research university located in Melbourne, Australia. Founded in 1853, it is Australia's second oldest university and the oldest in the state ...
), examined cells from the intestines of children with
gastroenteritis Gastroenteritis, also known as infectious diarrhea, is an inflammation of the Human gastrointestinal tract, gastrointestinal tract including the stomach and intestine. Symptoms may include diarrhea, vomiting, and abdominal pain. Fever, lack of ...
. Intestinal biopsies were taken at the Royal Children's Hospital in Melbourne, Australia, and sent to Ian Holmes and Brian Ruck (University of Melbourne) to be examined by electron-microscopy. Under the
electron microscope An electron microscope is a microscope that uses a beam of electrons as a source of illumination. It uses electron optics that are analogous to the glass lenses of an optical light microscope to control the electron beam, for instance focusing it ...
cells were seen to be infected with viruses, which were originally named "duovirus" because they were seen in the duodenum and had a double
capsid A capsid is the protein shell of a virus, enclosing its genetic material. It consists of several oligomeric (repeating) structural subunits made of protein called protomers. The observable 3-dimensional morphological subunits, which may or m ...
. The name "rotavirus" was later suggested by the Irishman, Thomas Henry Flewett, because of the round, wheel-like shape of virus particles. Rotaviruses cause diarrhoea and vomiting in young children and are a leading cause of death in the developing countries. Three thousand children are now hospitalised with rotavirus every year, down from 10,000 before the vaccine was introduced in 2007. Bishop said the invention of electron microscopy helped her make the discovery. The team's discovery led to a global effort to control of rotavirus. Bishop also published theoretical works about the patterns in the epidemiology of rotavirus infection. From 1983 to 1988, Bishop was Chair of the Committee on Diarrhoeal Diseases with the
World Health Organization The World Health Organization (WHO) is a list of specialized agencies of the United Nations, specialized agency of the United Nations which coordinates responses to international public health issues and emergencies. It is headquartered in Gen ...
(WHO).


Awards and honours

Bishop was made an
Officer of the Order of Australia The Order of Australia is an Australian honours and awards system, Australian honour that recognises Australian citizens and other persons for outstanding achievement and service. It was established on 14 February 1975 by Elizabeth II, Monarch ...
(AO) in the 1996 Queen's Birthday Honours in recognition of service to medical research, particularly for her contributions to the understanding of gastroenteritis in children.BISHOP, Ruth Frances AO
''It's an Honour'', 11 June 1996.
In the 2019 Queen's Birthday Honours she was promoted to
Companion of the Order of Australia The Order of Australia is an Australian honours and awards system, Australian honour that recognises Australian citizens and other persons for outstanding achievement and service. It was established on 14 February 1975 by Elizabeth II, Monarch ...
(AC) for "eminent service to global child health through the development of improved vaccines for paediatric gastroenteritis, and to medical research". In 2001, she was inducted to the Victorian Honour Roll of Women. In 2011, she received the
Prince Mahidol Award The Prince Mahidol Award () is an annual award for outstanding achievements in medicine and public health worldwide. The award is given by the Prince Mahidol Award Foundation, which was founded by the Thai Royal Family in 1992. Prince Mahidol ...
awarded by the Thai Royal Family for outstanding achievement in public health. Bishop was awarded the Florey Medal in 2013 for her discovery of rotavirus and subsequent work helping to develop a vaccine. The medal recognises significant achievements in biomedical research. This was the first time a woman was honoured with this award. In 2020, the Melbourne based Bio21 building announced Ruth Bishop as the namesake of their new imaging building, the "Ruth Bishop Building", housing the University of Melbourne's Ian Holmes Imaging Centre.


References

{{DEFAULTSORT:Bishop, Ruth 1933 births 2022 deaths Australian virologists Australian women scientists Officers of the Order of Australia Companions of the Order of Australia World Health Organization officials University of Melbourne alumni Academic staff of the University of Melbourne Australian officials of the United Nations Scientists from Melbourne People from Frankston, Victoria