Russel E. Kaufman is an American researcher who is president emeritus of

The Wistar Institute The Wistar Institute () is an independent, nonprofit research institution in biomedical science with special focuses in oncology, immunology, infectious disease, and vaccine research. Located on Spruce Street in the University City section of P ...

Philadelphia Philadelphia ( ), colloquially referred to as Philly, is the List of municipalities in Pennsylvania, most populous city in the U.S. state of Pennsylvania and the List of United States cities by population, sixth-most populous city in the Unit ...

. In addition to his administrative role at Wistar, Kaufman maintains a research program that focuses on the genetics behind various types of blood diseases and cancer. During his time in research, some of Kaufman's discoveries include the characterization of the β-globin genes and the discovery of the CD7 ligand, K12. Additionally, he has focused on the regulation of genes expressed in hematopoietic

stem cell In multicellular organisms, stem cells are undifferentiated or partially differentiated cells that can change into various types of cells and proliferate indefinitely to produce more of the same stem cell. They are the earliest type of cell ...

s and their progenitors. Kaufman is active in a number of Philadelphia regional organizations and national organizations related to cancer research. He has served as chair of the Greater Philadelphia Life Sciences Congress, a board member of the board of directors for the University City Science Center, an adviser to the

National Institutes of Health The National Institutes of Health (NIH) is the primary agency of the United States government responsible for biomedical and public health research. It was founded in 1887 and is part of the United States Department of Health and Human Service ...

, and an adviser to the

American Cancer Society The American Cancer Society (ACS) is a nationwide non-profit organization dedicated to eliminating cancer. The ACS publishes the journals ''Cancer'', '' CA: A Cancer Journal for Clinicians'' and '' Cancer Cytopathology''. History The society w ...

. In 2008, Kaufman received the Cancer Control Award from the American Cancer Society for his "exemplary individual achievements in the field of cancer control.". In 2012, the

Philadelphia Business Journal American City Business Journals, Inc. (ACBJ) is an American newspaper publisher based in Charlotte, North Carolina. ACBJ publishes ''The Business Journals'', which contains local business news for 44 markets in the United States with each market ...

named Kaufman Life Sciences CEO of the Year. Prior to taking his role at Wistar in 2002, Kaufman worked at

Duke University Medical Center Duke University Hospital is a 1062 -bed acute care facility and an academic tertiary care facility located in Durham, North Carolina, United States. Established in 1930, it is the flagship teaching hospital for the Duke University Health Sy ...

, where he served as chief resident, division chief of medical oncology, vice chair of the Department of Medicine, and vice dean for education and academic affairs.

Select publications

* Ge, Y., Azuma, R., Gekonge, B., Lopez-Coral, A., Xiao, M., Zhang, G., Xu, X., Montaner, L., Wei, Z., Herlyn, M., Wang, T., Kaufman, Russel E.: Induction of metallothionein expression during monocyte to melanoma-associated macrophage differentiation. Front. Biol 7(4): 359–367, 2012. * Wang, T., Ge, Y., Xiao, M., Lopez-Coral, A., Azuma, R., Somasundaram, R., Zhang, G., Wei, Z., Xu, X., Rauscher, FJ 3rd, Herlyn, M., Kaufman, R.E.: Melanoma-derived conditioned media efficiently induce the differentiation of monocytes to macrophages that display a highly invasive gene signature. Pigment Cell Melanoma Res 25:493-505, 2012. * Wang, T., Huang, C., Lopez-Coral, A., Slentz-Kesler, K.A., Xiao, M., Wherry, E.J., Kaufman, R.E.: K12/SECTM1, an interferon regulated molecule, synergizes with CD28 to costimulate human T cell proliferation. J Leukoc Biol 91:449-459, 2012. * Lam, G.K., Liao, H.X., Xue, Y., Alam, S.M., Scearce, R.M., Kaufman, R.E., Sempowski, G.D., Haynes, B.F.: Expression of the CD7 ligand K-12 in human thymic epithelial cells: regulation by IFN-gamma. J Clin Immunol 25:41-49, 2005. * Sempowski, G.D., Lee, D.M., Kaufman, R.E., Haynes, B.F.: Structure and function of the CD7 molecule. Crit Rev Immunol 19:331-348, 1999.

References

External links

Dr. Kaufman's lab page on The Wistar Institute's website
Cancer researchers Living people American health care chief executives Year of birth missing (living people) Searle Scholars Program recipients {{US-CEO-stub