Rozalyn (Roz) Anderson is a professor at the

University of Wisconsin School of Medicine and Public Health A university () is an institution of higher (or tertiary) education and research which awards academic degrees in several academic disciplines. ''University'' is derived from the Latin phrase ''universitas magistrorum et scholarium'', which ...

. She studies

aging Ageing ( BE) or aging ( AE) is the process of becoming older. The term refers mainly to humans, many other animals, and fungi, whereas for example, bacteria, perennial plants and some simple animals are potentially biologically immortal. In ...

and

caloric restriction Calorie restriction (caloric restriction or energy restriction) is a dietary regimen that reduces intake of energy from caloric foods & beverages without incurring malnutrition. "Reduce" can be defined relative to the subject's previous intake b ...

primate Primates are a diverse order (biology), order of mammals. They are divided into the Strepsirrhini, strepsirrhines, which include the lemurs, galagos, and lorisids, and the Haplorhini, haplorhines, which include the Tarsiiformes, tarsiers and ...

Education

Anderson received her bachelor's degree from

Trinity College, Dublin , name_Latin = Collegium Sanctae et Individuae Trinitatis Reginae Elizabethae juxta Dublin , motto = ''Perpetuis futuris temporibus duraturam'' (Latin) , motto_lang = la , motto_English = It will last i ...

and her Ph.D. in

biochemistry Biochemistry or biological chemistry is the study of chemical processes within and relating to living organisms. A sub-discipline of both chemistry and biology, biochemistry may be divided into three fields: structural biology, enzymology ...

from

University College Dublin University College Dublin (commonly referred to as UCD) ( ga, Coláiste na hOllscoile, Baile Átha Cliath) is a public research university in Dublin, Ireland, and a collegiate university, member institution of the National University of Ireland ...

. In 2000 she moved to

Harvard Medical School Harvard Medical School (HMS) is the graduate medical school of Harvard University and is located in the Longwood Medical and Academic Area, Longwood Medical Area of Boston, Massachusetts. Founded in 1782, HMS is one of the oldest medical schools ...

, Boston, Massachusetts for a post-doctoral fellowship with David Sinclair, where she studied caloric restriction and aging in

yeast Yeasts are eukaryotic, single-celled microorganisms classified as members of the fungus kingdom. The first yeast originated hundreds of millions of years ago, and at least 1,500 species are currently recognized. They are estimated to consti ...

. She began studying mammalian aging during a second post-doctoral fellowship with Richard Weindruch at the University of Wisconsin Institute on Aging and as an assistant scientist at the Wisconsin

National Primate Research Center National Primate Research Centers are a network of seven research programs in the United States funded by the National Institutes of Health to conduct biomedical research on primates. Each center is affiliated with a university or other host institu ...

. She is currently a professor at the University of Wisconsin in the Department of Medicine in the Division of Geriatrics and Gerontology. Since 2014, Anderson has also been affiliated with the Division of Endocrinology, Diabetes and Metabolism.

Research

In the Sinclair laboratory at Harvard Medical School, Anderson researched the regulation of the lifespan by calorie restriction in yeast, demonstrating that lifespan could be extended by genetic manipulation of the NAD⁺ salvage pathway, and that calorie restriction downregulates NAD⁺. Anderson worked as part of the University of Wisconsin team that demonstrated that caloric restriction has a beneficial effect in rhesus monkeys, improves survival, and lowers the incidence of diseases including diabetes, cancer, and cardiovascular disease over the course of nearly three decades. She continues to study caloric restriction, focusing on primate skeletal muscle, white adipose tissue, inflammation, mitochondrial dysfunction, and metabolic regulators of cancer growth. In a 2014 interview discussing the different results of the

National Institute of Aging The National Institute on Aging (NIA) is a division of the U.S. National Institutes of Health (NIH), located in Bethesda, Maryland. The NIA itself is headquartered in Baltimore, Maryland. The NIA leads a broad scientific effort to understand the ...

and University of Wisconsin

rhesus monkey The rhesus macaque (''Macaca mulatta''), colloquially rhesus monkey, is a species of Old World monkey. There are between six and nine recognised subspecies that are split between two groups, the Chinese-derived and the Indian-derived. Generally b ...

caloric restriction studies, Anderson points out that due to the experimental setup, both the control and experimental groups were calorie restricted to some degree, which explains why no significant improvement was found in the experimental group. She also points out that the two studies are more informative due to their differing designs than if they had been performed identically. In 2013, Anderson won the Nathan Shock New Investigator Award from the

Gerontological Society of America The Gerontological Society of America (GSA) is a multidisciplinary organization devoted to research and education in all aspects of gerontology: medical, biological, psychological and social. History and organization The Gerontological Society o ...

. From 2019-2021, Anderson served as the President of the American Aging Association. Anderson is the co-

editor-in-chief An editor-in-chief (EIC), also known as lead editor or chief editor, is a publication's editorial leader who has final responsibility for its operations and policies. The highest-ranking editor of a publication may also be titled editor, managing ...

of ''

The Journals of Gerontology ''The Journals of Gerontology'' are the first scientific journals on aging published in the United States. The publication is separated into four separate peer-reviewed scientific journals, each with its own editor, and published in two series. Th ...

'' Series A: Biological Sciences.

References

External links

YouTube lecture
{{DEFAULTSORT:Anderson, Rozalyn Year of birth missing (living people) Living people American women biologists University of Wisconsin–Madison faculty Place of birth missing (living people) Alumni of Trinity College Dublin Alumni of University College Dublin American women biochemists American women academics 21st-century American women scientists