Ronifibrate is a
fibrate
In pharmacology, the fibrates are a class of amphipathic carboxylic acids and esters. They are derivatives of fibric acid (phenoxyisobutyric acid). They are used for a range of metabolic disorders, mainly hypercholesterolemia (high cholesterol), ...
, a
hypolipidemic agent Lipid-lowering agents, also sometimes referred to as hypolipidemic agents, cholesterol-lowering drugs, or antihyperlipidemic agents are a diverse group of pharmaceuticals that are used to lower the level of lipids and lipoproteins such as cholestero ...
. It is a combined
ester
In chemistry, an ester is a compound derived from an oxoacid (organic or inorganic) in which at least one hydroxyl group () is replaced by an alkoxy group (), as in the substitution reaction of a carboxylic acid and an alcohol. Glycerides ...
of
clofibric acid
Clofibric acid is a biologically active metabolite of the lipid-lowering drugs clofibrate, etofibrate and theofibrate with the molecular formula C10H11ClO3. It has been found in the environment following use of these drugs, for example in Swiss l ...
and
niacin
Niacin, also known as nicotinic acid, is an organic compound and a form of vitamin B3, an essential human nutrient. It can be manufactured by plants and animals from the amino acid tryptophan. Niacin is obtained in the diet from a variet ...
(nicotinic acid) with
1,3-propanediol. In the body, the ester is
split
Split(s) or The Split may refer to:
Places
* Split, Croatia, the largest coastal city in Croatia
* Split Island, Canada, an island in the Hudson Bay
* Split Island, Falkland Islands
* Split Island, Fiji, better known as Hạfliua
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to 1,3-propanediol and both acids which work in the same way, lowering
lipids
Lipids are a broad group of naturally-occurring molecules which includes fats, waxes, sterols, fat-soluble vitamins (such as vitamins A, D, E and K), monoglycerides, diglycerides, phospholipids, and others. The functions of lipids includ ...
in blood.
References
2-Methyl-2-phenoxypropanoic acid derivatives
Prodrugs
Chloroarenes
Nicotinate esters
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