Professor Rolf Müller (born August 13, 1953) is a German
molecular biologist
Molecular biology is a branch of biology that seeks to understand the molecule, molecular basis of biological activity in and between Cell (biology), cells, including biomolecule, biomolecular synthesis, modification, mechanisms, and interactio ...
and professor within the Institute of Molecular Biology and Tumor Research,
University of Marburg
The Philipps University of Marburg () is a public research university located in Marburg, Germany. It was founded in 1527 by Philip I, Landgrave of Hesse, which makes it one of Germany's oldest universities and the oldest still operating Prote ...
. He is working in the area of
molecular oncology
Molecular oncology is an interdisciplinary medical specialty at the interface of medicinal chemistry and oncology that refers to the investigation of the chemistry of cancer and tumors at the molecule, molecular scale. Also the development and app ...
with a focus on
human ovarian cancer. He is particularly interested in transcriptional networks, therapy resistance, the
tumor micro environment and tumor metabolism. This work is intimately linked to the function of the nuclear receptor
PPARβ/δ and its potential as a drug target.
Education
In 1979, he received a Ph.D. from the Institute of Cell Biology and Tumor Research,
University of Essen
The University of Duisburg-Essen () is a public research university in North Rhine-Westphalia, Germany. In the 2019 ''Times Higher Education World University Rankings'', the university was awarded 194th place in the world. It was originally ...
with a thesis on "Immunological quantitation of 06-ethylguanine in DNA after alkylation by the carcinogen N-ethyl-N-nitrosourea in vivo and in vitro”, From 1979 to 1981 he was a Research assistant there, and then from 1981–1983 was a postdoctoral fellow in the laboratory of
I. M. Verma, Tumor Virus Laboratory,
The Salk Institute for Biological Studies, San Diego, California (supported by a DFG fellowship)
Professional career
From 1983–1988 he became a group leader at the
European Molecular Biology Laboratory (EMBL), Heidelberg, and in 1987 was appointed full professor of molecular biology,
Philipps University of Marburg
Philipps is an English language, English, Dutch language, Dutch, and German language, German surname meaning "lover of horses". Derivative, patronym, of the more common ancient Greek name "Philippos and Philippides." Notable people with this surnam ...
. For the period 1991–1996, he was also Research group leader, ZMBH,
University of Heidelberg
Heidelberg University, officially the Ruprecht Karl University of Heidelberg (; ), is a public university, public research university in Heidelberg, Baden-Württemberg, Germany. Founded in 1386 on instruction of Pope Urban VI, Heidelberg is List ...
.
Awards and honors
He was awarded the
Leibniz Prize (1991) and the German Cancer Award (2000) for his discoveries on the regulation of gene expression by oncogenic signaling pathways and cell cycle regulation. His scientific work has been published in more than 200 articles so far.
References
{{DEFAULTSORT:Muller, Rolf
20th-century German biologists
21st-century German biologists
German molecular biologists
Academic staff of the University of Marburg
University of Duisburg-Essen alumni
1953 births
Living people