Robert Thomas Sauer (born 13 July 1948) is an American

biochemist Biochemists are scientists who are trained in biochemistry. They study chemical processes and chemical transformations in living organisms. Biochemists study DNA, proteins and Cell (biology), cell parts. The word "biochemist" is a portmanteau of ...

who is the Salvador E. Luria Professor of Biology at the

Massachusetts Institute of Technology The Massachusetts Institute of Technology (MIT) is a Private university, private research university in Cambridge, Massachusetts, United States. Established in 1861, MIT has played a significant role in the development of many areas of moder ...

Early life and education

Bob Sauer was born in

Cornwall, New York Cornwall is a Town (New York), town in Orange County, New York, United States, approximately north of New York City on the western shore of the Hudson River. As of the 2020 census, the population was at 12,884. Cornwall has become a Commuter t ...

, in the

Hudson Valley The Hudson Valley or Hudson River Valley comprises the valley of the Hudson River and its adjacent communities in the U.S. state of New York (state), New York. The region stretches from the Capital District (New York), Capital District includi ...

area of

New York New York most commonly refers to: * New York (state), a state in the northeastern United States * New York City, the most populous city in the United States, located in the state of New York New York may also refer to: Places United Kingdom * ...

. He attended

Amherst College Amherst College ( ) is a Private college, private Liberal arts colleges in the United States, liberal arts college in Amherst, Massachusetts, United States. Founded in 1821 as an attempt to relocate Williams College by its then-president Zepha ...

in Massachusetts as an undergraduate and earned his bachelor's degree in

biophysics Biophysics is an interdisciplinary science that applies approaches and methods traditionally used in physics to study biological phenomena. Biophysics covers all scales of biological organization, from molecular to organismic and populations ...

in 1972. He received his PhD in

Biochemistry Biochemistry, or biological chemistry, is the study of chemical processes within and relating to living organisms. A sub-discipline of both chemistry and biology, biochemistry may be divided into three fields: structural biology, enzymology, a ...

and

Molecular Biology Molecular biology is a branch of biology that seeks to understand the molecule, molecular basis of biological activity in and between Cell (biology), cells, including biomolecule, biomolecular synthesis, modification, mechanisms, and interactio ...

from

Harvard University Harvard University is a Private university, private Ivy League research university in Cambridge, Massachusetts, United States. Founded in 1636 and named for its first benefactor, the History of the Puritans in North America, Puritan clergyma ...

in 1979.

Academic career

Sauer joined the faculty at the

in 1978, a year before he completed his PhD. He has remained at MIT for his entire academic career, becoming a

full professor Professor (commonly abbreviated as Prof.) is an academic rank at universities and other post-secondary education and research institutions in most countries. Literally, ''professor'' derives from Latin as a 'person who professes'. Professors ...

in 1987 and the Edwin C. Whitehead Professor in 1991. Sauer assumed his current appointment as the Salvador E. Luria Professor of Biology in 1999. He has held a number of service roles at MIT and spent five years, from 1999 to 2004, as the head of the biology department. He was the president of the

Protein Society The Protein Society is an international, not-for-profit, scholarly society with the mission to provide forums for the advancement of research into protein structure, function, design and applications. History The Protein Society was founded in ...

from 1997 to 1999. Sauer was elected to the

American Academy of Arts and Sciences The American Academy of Arts and Sciences (The Academy) is one of the oldest learned societies in the United States. It was founded in 1780 during the American Revolution by John Adams, John Hancock, James Bowdoin, Andrew Oliver, and other ...

in 1996 and to both the

American Academy of Microbiology American(s) may refer to: * American, something of, from, or related to the United States of America, commonly known as the "United States" or "America" ** Americans, citizens and nationals of the United States of America ** American ancestry, p ...

and the

United States National Academy of Sciences The National Academy of Sciences (NAS) is a United States nonprofit, non-governmental organization. NAS is part of the National Academies of Sciences, Engineering, and Medicine, along with the National Academy of Engineering (NAE) and the Nati ...

in 1996. He has received both the

Hans Neurath Hans Neurath (October 29, 1909 – April 2002) was a biochemist, a leader in protein chemistry, and the founding chairman of the Department of Biochemistry at the University of Washington in Seattle. He was born in Vienna, Austria, and received ...

Award and the

Stein Stein may refer to: Places Austria * Stein, a neighbourhood of Krems an der Donau, Lower Austria * Stein, Styria, a municipality in the district of Fürstenfeld, Styria * Stein (Lassing), a village in the district of Liezen, Styria * Stein a ...

and

Moore Moore may refer to: Language * Mooré language, spoken in West Africa People * Moore (surname) ** List of people with surname Moore * Moore Crosthwaite (1907–1989), a British diplomat and ambassador * Moore Disney (1765–1846), a senior ...

Award from the Protein Society.

Research

Sauer's research group has focused on

protein structure Protein structure is the three-dimensional arrangement of atoms in an amino acid-chain molecule. Proteins are polymers specifically polypeptides formed from sequences of amino acids, which are the monomers of the polymer. A single amino acid ...

and

folding Fold, folding or foldable may refer to: Arts, entertainment, and media * ''Fold'' (album), the debut release by Australian rock band Epicure * Fold (poker), in the game of poker, to discard one's hand and forfeit interest in the current pot *Abov ...

, and the relationship of structure to the molecular mechanisms of intermolecular interactions such as DNA binding. His group has made significant contributions to the study of

protein degradation Proteolysis is the breakdown of proteins into smaller polypeptides or amino acids. Protein degradation is a major regulatory mechanism of gene expression and contributes substantially to shaping mammalian proteomes. Uncatalysed, the hydrolysis o ...

and its regulation in living cells.

References

{{DEFAULTSORT:Sauer, Robert American biochemists Massachusetts Institute of Technology School of Science faculty Harvard University alumni Amherst College alumni Members of the United States National Academy of Sciences Fellows of the American Academy of Arts and Sciences Living people 1948 births People from Cornwall, New York