Robert McCarrison
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Major-General Sir Robert McCarrison, CIE, FRCP (15 March 1878 – 18 May 1960) was a
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physician A physician, medical practitioner (British English), medical doctor, or simply doctor is a health professional who practices medicine, which is concerned with promoting, maintaining or restoring health through the Medical education, study, Med ...
and
nutritionist A nutritionist is a person who advises others on matters of food and Human nutrition, nutrition and their impacts on health. Some people specialize in particular areas, such as sports nutrition, public health, or animal nutrition, among other disci ...
in the
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, who was made a Companion of the Indian Empire (CIE) in 1923, (See p.3946 for list heading) received a knighthood in July 1933, and was appointed as Honourable Physician to the King in 1935. McCarrison was born in
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, in
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,
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. He qualified in Medicine at
Queen's College, Belfast The Queen's University of Belfast, commonly known as Queen's University Belfast (; abbreviated Queen's or QUB), is a public research university in Belfast, Northern Ireland, United Kingdom. The university received its charter in 1845 as part of ...
in 1900. He joined the
Indian Medical Service The Indian Medical Service (IMS) was a military medical service in British India, which also had some civilian functions. It served during the two World Wars, and remained in existence until the independence of India in 1947. Many of its officer ...
and was posted as Medical Officer to Indian troops guarding the mountainous Northern Frontiers. He was promoted to Captain in January 1904, to Major in July 1912, Lieutenant-Colonel in January 1918, (List heading: "To be Brevet Lieutenant-Colonerl" is on p.10) Colonel from 1929, and to Major-General in July 1933. He retired from the Indian Medical Service on 19 August 1935. McCarrison's research in India on the cause of
goitre A goitre (British English), or goiter (American English), is a swelling in the neck resulting from an enlarged thyroid gland. A goitre can be associated with a thyroid that is not functioning properly. Worldwide, over 90% of goitre cases are ...
won widespread recognition and in 1913 he was promoted to do research. In 1928 he became Director of Nutritional Research in India, where he remained until his retirement from the Indian Medical Service in 1935, when he returned to
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, settling at
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.


Pioneer in nutrition research

McCarrison carried out the very first experiments to demonstrate the effect of
nutrition Nutrition is the biochemistry, biochemical and physiology, physiological process by which an organism uses food and water to support its life. The intake of these substances provides organisms with nutrients (divided into Macronutrient, macro- ...
on the
epidemiology Epidemiology is the study and analysis of the distribution (who, when, and where), patterns and Risk factor (epidemiology), determinants of health and disease conditions in a defined population, and application of this knowledge to prevent dise ...
of disease. McCarrison is credited with being the first to experimentally demonstrate the effect of deficient dietaries upon animal tissues and organs. He also carried out human experiments aimed at identifying the cause of goitre, and included himself as one of the experimental subjects. Much of McCarrison's work was pioneering. His 1921 book ''Studies in Deficiency Disease'' was considered notable at the time, being published at a time when knowledge of vitamins and their role in nutrition was crystallizing. McCarrison himself noted that prior to publication of his studies on the pathogenesis of deficiency disease "no systemic ''post-mortem'' examination of animals fed on food deficient in
vitamin B B vitamins are a class of water-soluble vitamins that play important roles in cell metabolism and synthesis of red blood cells. They are a chemically diverse class of compounds. Dietary supplements containing all eight are referred to as a vita ...
had ever been made; the histopathological effects of such food on the various systems of the body were wholly unknown; above all, its effects on the gastro-intestinal tract and the organs of digestion and assimilation, and the significance of these effects for clinical medicine, were wholly unsuspected". At age 23, McCarrison went to India, where he spent 30 years on nutritional problems.. Retrieved 12 August 2010 He attained the rank of major-general in the Indian Medical Service, and founded the Nutritional Research Laboratories in
Coonoor Coonoor (), is a taluk and a municipal town of the Nilgiris district in the Indian state of Tamil Nadu. As of 2011, the town had a population of 45,494. The town sits at the south-east corner of the Nilgiri plateau, and at the head of the Coonoo ...
. After retiring from the Indian Medical Service in 1935, he gave a series of Cantor lectures at the Royal Society of Arts, about the influence of diet on health. This comprised three lectures delivered on successive Mondays at the Society. The first lecture focused on the processes of nutrition; the second, on food essentials and their relationship to bodily structure and function; the third on disease prevention and physique improvement by attention to diet. The lectures were subsequently published in book form under the title ''Nutrition and Health'', and at the time of the third edition in 1962, were still not seen as "dated", with the advances of the preceding 25 years largely filling the details of the principles previously recognised by McCarrison. "McCarrison's work on goitre, cretinism, and
thyroid The thyroid, or thyroid gland, is an endocrine gland in vertebrates. In humans, it is a butterfly-shaped gland located in the neck below the Adam's apple. It consists of two connected lobes. The lower two thirds of the lobes are connected by ...
, begun in the western Himalayas in 1902, generated scores of scientific publications during the following thirty-five years", While McCarrison's work is often considered the start of serious studies of goitre and cretinism in
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, it was preceded by that of Commissioner
David Scott David Randolph Scott (born June 6, 1932) is an American retired test pilot and NASA astronaut who was the List of Apollo astronauts#People who have walked on the Moon, seventh person to walk on the Moon. Selected as part of the NASA Astronaut ...
at Rangur in north-east India around 1825, and was investigated by Mountford Bramley at
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in 1832. In 1918, McCarrison founded the ''Beri-Beri Enquiry Unit'' in a single room laboratory at the
Pasteur Institute The Pasteur Institute (, ) is a French non-profit private foundation dedicated to the study of biology, micro-organisms, diseases, and vaccines. It is named after Louis Pasteur, who invented pasteurization and vaccines for anthrax and rabies. Th ...
in Conoor, India. He was invalided to Britain from 1920–1922, and in 1923 the enquiry was axed on financial grounds. It was restored two years later as the ''Deficiency Disease Inquiry'', which McCarrison headed from 1925-1929. Around 1928-29, this developed further into the Nutrition Research Laboratories (NRL. Renamed the
National Institute of Nutrition The National Institute of Nutrition (NIN) is an Indian public health, nutrition and translational research centre located in Hyderabad, India. The institute is one of the oldest research centres in India, and the largest centre, under the India ...
in 1969), with McCarrison as its first director, until his retirement in 1935. In 1926, as head of the ''Deficiency Diseases Inquiry'', McCarrison submitted written and oral evidence on
malnutrition Malnutrition occurs when an organism gets too few or too many nutrients, resulting in health problems. Specifically, it is a deficiency, excess, or imbalance of energy, protein and other nutrients which adversely affects the body's tissues a ...
to the ''Royal Commission on Agriculture in India''. (Full text at Internet Archive The primary objective of McCarrison's submission was to indicate the significance of malnutrition "as a cause of physical inefficiency and ill-health among the masses in India"; the relationship between nutrition and agriculture; and "the necessity for closer co-ordination of nutritional, medical, veterinary and agricultural research" in India.McCarrison, Lieut.-Colonel R (1928), p.95 McCarrison's submission had impact. "A decade later, when the Commission's chairman,
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, became Viceroy of India he showed a personal interest in nutrition, pushing it to the top of the research agenda. In 1936 a Nutrition Advisory Committee was established and roughly a tenth of IRFA's annual grants went to fund nutrition research at Coonoor and
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".


Retirement from India

After
the Second World War World War II or the Second World War (1 September 1939 – 2 September 1945) was a global conflict between two coalitions: the Allies and the Axis powers. Nearly all of the world's countries participated, with many nations mobilising ...
, from 1945 to 1955, McCarrison served as director of postgraduate
medical education Medical education is vocational education, education related to the practice of being a medical practitioner, including the initial training to become a physician (i.e., medical school and internship (medical), internship) and additional trainin ...
at
Oxford University The University of Oxford is a collegiate research university in Oxford, England. There is evidence of teaching as early as 1096, making it the oldest university in the English-speaking world and the second-oldest continuously operating u ...
.


Personal life

In 1906 he married Helen Stella Johnston, to whom he was still married at the time of his death.


Legacy

* The National Institute of Nutrition in
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, India, continues to pay tribute to is origins in 1928 under McCarrison. * McCarrison is grouped, along with Sir Albert Howard and
Richard St. Barbe Baker Richard St. Barbe Baker (9 October 1889 – 9 June 1982) was an English biologist and botanist, environmental activist and author, who contributed greatly to worldwide reforestation efforts. As a leader, he founded an organisation, Men of ...
, as one of three progenitors of the
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movement.


McCarrison Society

In 1966, a group of doctors, dentists and veterinarians, interested in the promotion of nutrition and health, founded the McCarrison Society in honour of his efforts, with a
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group established in 1981 due to both travel logistics and differing needs in the Scottish population. The Society aims "to assemble scientific knowledge on nutrition and health that is free from economic and political pressures with the object of securing the physical and mental health of future generations". The society meetings sometimes raise questions with elusive answers, with speakers presenting material based on scanty, often anectdotal data, inviting criticism that it is "a gathering of cranks". However, "one answer to that criticism is that speakers at MCarrison meetings tend to be rather well qualified. But the main point is that the society has a way of asking questions about the environment - what are we doing to it and what it is doing to us - that are of profound importance". The journal "Nutrition and Health" is the official journal of the McCarrison Society and is listed in PUBMED. The journal was started by members in 1978 with the objective of publishing peer reviewed scientific work and reviews on nutrition and health from academic research workers who were independent of the food and agricultural industries or those with a conflict of interest. The society's website summarises McCarrison's work thus:
His researches were extensive; they included work on the newly discovered
vitamins Vitamins are organic molecules (or a set of closely related molecules called vitamers) that are essential to an organism in small quantities for proper metabolic function. Essential nutrients cannot be synthesized in the organism in suff ...
and on the contrasting disease patterns in the
Indian subcontinent The Indian subcontinent is a physiographic region of Asia below the Himalayas which projects into the Indian Ocean between the Bay of Bengal to the east and the Arabian Sea to the west. It is now divided between Bangladesh, India, and Pakista ...
. He demonstrated how many common diseases increasingly prevalent in industrial societies were caused simply by diets made defective by extensive food processing, often with the use of chemical additives. He deplored the universal consumption in Britain and America of refined white flour, instead of halite flour, and the substitution of canned, preserved and artificially sweetened products for fresh natural food. McCarrison's work was widely published in the medical press. He was honoured for his discoveries, but completely ignored by government and the medical profession at a time when medical thought was absorbed in the study of disease rather than on prevention and the promotion of health.


Publications

The following is a selection of works published by McCarrison. To avoid duplication, this does not include works cited, which are to be found in the References section. * * * * *
download page
* * * . Retrieved 12 August 2010 * * (Full text at Internet Archive). * (Online registration to view articles is free). * * * * * * * (1945 photo-lithographic reproduction by Lee Foundation for Nutritional Research. Full text at Internet Archive). ** * * (Pay-per-view access). * * * * * * * * . Retrieved 12 August 2010 *
JUSTOR link
* * * * * * * * * * * } * * *


Explanatory notes

a. The bulk of McCarrison's work appears to have been published in the ''
British Medical Journal ''The BMJ'' is a fortnightly peer-reviewed medical journal, published by BMJ Publishing Group Ltd, which in turn is wholly-owned by the British Medical Association (BMA). ''The BMJ'' has editorial freedom from the BMA. It is one of the world ...
'' (BMJ), although he did publish in other journals, such as ''
JAMA ''JAMA'' (''The Journal of the American Medical Association'') is a peer-reviewed medical journal published 48 times a year by the American Medical Association. It publishes original research, reviews, and editorials covering all aspects of b ...
'' and ''
The Lancet ''The Lancet'' is a weekly peer-reviewed general medical journal, founded in England in 1823. It is one of the world's highest-impact academic journals and also one of the oldest medical journals still in publication. The journal publishes ...
'', amongst others. Some publications are also found in the ''
Proceedings of the Royal Society of Medicine The ''Journal of the Royal Society of Medicine'' is a peer-reviewed medical journal. It is the flagship journal of the Royal Society of Medicine, located in London, with full editorial independence. Its continuous publication history dates back to ...
''. Free access to publications ''BMJ'' and the ''Proceedings'' is to be found in the external links section. Some of McCarrison's publications listed are from those journals, but links were not located at time of listing. They should however, be available at these websites, along with other publications by or about McCarrison from those two journals which have not been located or listed. b. This letter is by the "nominal overseer" of McCarrison's last salaried post. It contains particularly insightful commentary on the contribution of McCarrison at a time of significant change in the existing university and medical institutions of the UK. c. The author of this obituary letter on McCarrison is identified only as "N.C.P.", which are also the initials of N.C. Penrose, author of a 1951 letter defending the legacy of McCarrison's earlier works. d. A book review of the 1953 edition is cited in this article, hence the listing. However, there have been other publications of this book both before and since. A publication from 1944 (''Nutrition and National Health'') is to be found via web searches comprising the same lecture and essay collection. And publications in 1961 and 1982, under ''Nutrition and Health'', are also to be found. A new edition was produced in 2010, and may found at Lulu, a Print on Demand /
Self-Publishing Self-publishing is an author-driven publication of any media without the involvement of a third-party publisher. Since the advent of the internet, self-published usually depends upon digital platforms and print-on-demand technology, ranging fro ...
service.


Citations


General and cited references

The following works discuss aspects of the life and work of Robert McCarrison. * * ebook * * * * . Retrieved 11 August 2010. * retrieved 11 August 2010 * * ** * * *


External links


''British Medical Journal'' online archive
Access to articles is free, but requires a simple registration.
RSM journal archives back to 1809 at PubMed Central
Contains archives of the Proceedings of the Royal Society of Medicine, access to which is free
McCarrison Society for Nutrition and Health - homepage
{{DEFAULTSORT:Maccarrison, Robert 1878 births 1960 deaths 20th-century medical doctors from Northern Ireland 20th-century Irish non-fiction writers British Indian Army generals British nutritionists Companions of the Order of the Indian Empire Diet food advocates Dietitians Fellows of the Royal College of Physicians Indian Army personnel of World War I Indian Medical Service officers Knights Bachelor Medical doctors from County Armagh People from Portadown Military doctors from Northern Ireland