Robert Goldman (born 1959 in

Rochester, New York Rochester () is a city in the U.S. state of New York, the seat of Monroe County, and the fourth-most populous in the state after New York City, Buffalo, and Yonkers, with a population of 211,328 at the 2020 United States census. Located i ...

) is an American inventor responsible for pioneering technology in digital media as well as

cancer treatment Cancer can be treated by surgery, chemotherapy, radiation therapy, hormonal therapy, targeted therapy (including immunotherapy such as monoclonal antibody therapy) and synthetic lethality, most commonly as a series of separate treatments (e.g. ...

Digital audio download patents

In the early 1990s, Goldman developed and patented technologies for digital audio systems wherein music could be stored, browsed, downloaded and purchased from digital databases. These technologies are a way for enabling digital music downloads on web sites. In 1999 Goldman launched the company GetMedia, Inc. to support this technology, and subsequently sold his intellectual property to

Intellectual Ventures Intellectual Ventures is an American private equity company that centers on the development and licensing of intellectual property. Intellectual Ventures is one of the top-five owners of U.S. patents, as of 2011. Its business model focuses on ...

, an IP licensing company, for an undisclosed sum.

Cancer treatment catheter

In 2002, Goldman launched the company, Vascular Designs, where he developed an innovative medical device, the IsoFlow infusion

catheter In medicine, a catheter (/ˈkæθətər/) is a thin tube made from medical grade materials serving a broad range of functions. Catheters are medical devices that can be inserted in the body to treat diseases or perform a surgical procedure. Cat ...

. An important application for the IsoFlow catheter may be in the treatment of

cancer Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. These contrast with benign tumors, which do not spread. Possible signs and symptoms include a lump, abnormal bl ...

. Goldman invented the device in an attempt to save his own sister, Amy Cohen, from

colon cancer Colorectal cancer (CRC), also known as bowel cancer, colon cancer, or rectal cancer, is the development of cancer from the colon or rectum (parts of the large intestine). Signs and symptoms may include blood in the stool, a change in bowel ...

. The IsoFlow is a dual balloon catheter designed to isolate a specific treatment region within the body from blood flow. It allows the infusion of fluids into the region and the

perfusion Perfusion is the passage of fluid through the circulatory system or lymphatic system to an organ or a tissue, usually referring to the delivery of blood to a capillary bed in tissue. Perfusion is measured as the rate at which blood is deliv ...

of blood past the region to keep the blood flow intact during treatment. One of the many unique features of the IsoFlow infusion catheter is the ability to deliver medications sideways while using pressure to push the medications into the targeted area. The IsoFlow catheter is inserted over a guide wire for precise positioning within a patient’s body. Once in place, medication is infused and isolated when both of the catheter’s balloons are simultaneously inflated using fluid via a single inflation lumen. Vascular Designs secured U.S.

Food and Drug Administration The United States Food and Drug Administration (FDA or US FDA) is a federal agency of the Department of Health and Human Services. The FDA is responsible for protecting and promoting public health through the control and supervision of food ...

(FDA) 510(k) marketing clearance for its IsoFlow catheter as a Class II

medical device A medical device is any device intended to be used for medical purposes. Significant potential for hazards are inherent when using a device for medical purposes and thus medical devices must be proved safe and effective with reasonable assur ...

in May 2009. With the IsoFlow catheter’s design, medications can be pushed into areas that could not previously be treated directly. According to numerous studies, this type of approach to delivery can increase drug concentrations at targeted sites while reducing systemic exposure, potentially improving treatment outcomes.Collins, JM (1984).
Pharmacologic rationale for regional drug delivery
Page 498-504. ''

Journal of Clinical Oncology The ''Journal of Clinical Oncology'' is a peer-reviewed medical journal published 3 times a month by the Lippincott Williams & Wilkins. It covers research on all aspects of clinical oncology. The journal was established in 1983 and the editor-in-c ...

References

External links

Vascular Designs
* Ponce, David (September 16, 2009).
The IsoFlow Infusion Catheter Allows For More Precise, Powerful Cancer Treatment
OhGizmo.com * Foremski, Tom (September 2, 2009).
How a software engineer tried to save his sister and invented a breakthrough medical device
ZDNet.com * Video Describing IsoFlow Procedur
youtube.com
{{DEFAULTSORT:Goldman, Robert Living people American inventors 1959 births