RNase D is one of the seven

exoribonuclease An exoribonuclease is an exonuclease ribonuclease, which are enzymes that degrade RNA by removing terminal nucleotides from either the 5' end or the 3' end of the RNA molecule. Enzymes that remove nucleotides from the 5' end are called ''5'-3 ...

s identified in ''

E. coli ''Escherichia coli'' ( )Wells, J. C. (2000) Longman Pronunciation Dictionary. Harlow ngland Pearson Education Ltd. is a gram-negative, facultative anaerobic, rod-shaped, coliform bacterium of the genus ''Escherichia'' that is commonly foun ...

''. It is a 3'-5' exoribonuclease which has been shown to be involved in the 3' processing of various stable RNA molecules. RNase D has homologues in many other organisms like eubacteria and eukaryotes, and has been shown to contribute to the 3' maturation of several stable RNAs. When a part of another larger protein has a

domain A domain is a geographic area controlled by a single person or organization. Domain may also refer to: Law and human geography * Demesne, in English common law and other Medieval European contexts, lands directly managed by their holder rather ...

that is very similar to RNase D, this is called an RNase D domain.

References

External links

Crystal structure of ''E. coli'' RNase D at the RCSB Protein Data Bank
Ribonucleases EC 3.1.13 {{3.1-enzyme-stub