Revefenacin
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Revefenacin, sold under the brand name Yupelri, is a
medication Medication (also called medicament, medicine, pharmaceutical drug, medicinal product, medicinal drug or simply drug) is a drug used to medical diagnosis, diagnose, cure, treat, or preventive medicine, prevent disease. Drug therapy (pharmaco ...
for the treatment of
chronic obstructive pulmonary disease Chronic obstructive pulmonary disease (COPD) is a type of progressive lung disease characterized by chronic respiratory symptoms and airflow limitation. GOLD defines COPD as a heterogeneous lung condition characterized by chronic respiratory s ...
(COPD). It was approved for use in the United States in 2018. It was developed by Theravance Biopharma and is marketed by
Mylan Mylan N.V. was a global generic and specialty pharmaceuticals company. In November 2020, Mylan merged with Upjohn, Pfizer's off-patent medicine division, to form Viatris. Previously, the company was domiciled in the Netherlands, with principa ...
. Revefenacin is formulated as a solution that is nebulized and inhaled. Revefenacin is a
bronchodilator A bronchodilator or broncholytic (although the latter occasionally includes secretory inhibition as well) is a substance that dilates the bronchi and bronchioles, decreasing resistance in the respiratory airway and increasing airflow to the lun ...
that exerts its effect as a long-acting
muscarinic antagonist A muscarinic acetylcholine receptor antagonist, also simply known as a muscarinic antagonist or as an antimuscarinic agent, is a type of anticholinergic drug that blocks the activity of the muscarinic acetylcholine receptors (mAChRs). The muscarin ...
.


Society and culture


Brand names

In some countries, Yupelri is marketed by
Viatris Viatris Inc. is an American global pharmaceutical and healthcare corporation headquartered in Canonsburg, Pennsylvania. The corporation was formed through the merger of Mylan and Upjohn, a legacy division of Pfizer, on November 16, 2020. The ...
after Upjohn merged with Mylan to create Viatris.


References

{{Portal bar , Medicine Drugs acting on the respiratory system Piperidines Benzamides Carbamates Biphenyls Bronchodilators Muscarinic antagonists