Revaprazan (trade name Revanex) is a drug that reduces
gastric acid
Gastric acid, gastric juice, or stomach acid is a digestive fluid formed within the stomach lining. With a pH between 1 and 3, gastric acid plays a key role in digestion of proteins by activating digestive enzymes, which together break down the ...
secretion which is used for the treatment of
gastritis
Gastritis is inflammation of the lining of the stomach. It may occur as a short episode or may be of a long duration. There may be no symptoms but, when symptoms are present, the most common is upper abdominal pain (see dyspepsia). Other poss ...
. It acts as an acid pump antagonist (
potassium-competitive acid blocker Proton pump inhibitors (PPIs) block the gastric hydrogen potassium ATPase (H+/K+ ATPase) and inhibit gastric acid secretion. These drugs have emerged as the treatment of choice for acid-related diseases, including gastroesophageal reflux disease (G ...
). Revaprazan is approved for use in South Korea,
but is not approved in Europe or the United States.
References
Proton-pump inhibitors
Anilines
Organofluorides
Aminopyrimidines
Tetrahydroisoquinolines
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