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The Medical Renaissance, from around 1400 to 1700, was a period of progress in European
medical Medicine is the science and Praxis (process), practice of caring for patients, managing the Medical diagnosis, diagnosis, prognosis, Preventive medicine, prevention, therapy, treatment, Palliative care, palliation of their injury or disease, ...
knowledge, with renewed interest in the ideas of the
ancient Greek Ancient Greek (, ; ) includes the forms of the Greek language used in ancient Greece and the classical antiquity, ancient world from around 1500 BC to 300 BC. It is often roughly divided into the following periods: Mycenaean Greek (), Greek ...
, Roman civilizations and
Islamic medicine In the history of medicine, "Islamic medicine", also known as "Arabian medicine" is the science of medicine developed in the Middle East, and usually written in Arabic, the ''lingua franca'' of Islamic civilization. Islamic medicine adopted, s ...
, following the translation into Medieval Latin of many works from these societies. Medical discoveries during the Medical Renaissance are credited with paving the way for modern medicine.


Background

The Medical Renaissance began in the early 16th century. Medical researchers continued their Renaissance-evoked practices into the late 17th century. Progress made during the Medical Renaissance depended on several factors. Printed books based on
movable type Movable type (US English; moveable type in British English) is the system and technology of printing and typography that uses movable Sort (typesetting), components to reproduce the elements of a document (usually individual alphanumeric charac ...
, adopted in Europe from the middle of the 15th century, allowed the diffusion of medical ideas and anatomical diagrams. Linacre,
Erasmus Desiderius Erasmus Roterodamus ( ; ; 28 October c. 1466 – 12 July 1536), commonly known in English as Erasmus of Rotterdam or simply Erasmus, was a Dutch Christian humanist, Catholic priest and Catholic theology, theologian, educationalist ...
, Leonicello and Sylvius are among the list of the first scholars most credited for the starting of the Medical Renaissance. Following after is
Andreas Vesalius Andries van Wezel (31 December 1514 – 15 October 1564), latinized as Andreas Vesalius (), was an anatomist and physician who wrote '' De Humani Corporis Fabrica Libri Septem'' (''On the fabric of the human body'' ''in seven books''), which is ...
's publication of ''
De humani corporis fabrica ''De Humani Corporis Fabrica Libri Septem'' (Latin, "On the Fabric of the Human Body in Seven Books") is a set of books on human anatomy written by Andreas Vesalius (1514–1564) and published in 1543. It was a major advance in the history of a ...
'' (On the Fabric of the Human body) in 1543. Better knowledge of the original writings of
Galen Aelius Galenus or Claudius Galenus (; September 129 – AD), often Anglicization, anglicized as Galen () or Galen of Pergamon, was a Ancient Rome, Roman and Greeks, Greek physician, surgeon, and Philosophy, philosopher. Considered to be one o ...
in particular, developed into the
learned medicine Learned medicine is the European medical tradition in the Early Modern period, when it experienced the tension between the texts derived from ancient Greek medicine, particularly by followers of the teachings attributed to Hippocrates and those of ...
tradition through the more open attitudes of Renaissance humanism. Religious control of the teachings of the medical profession and universities diminished, and
dissection Dissection (from Latin ' "to cut to pieces"; also called anatomization) is the dismembering of the body of a deceased animal or plant to study its anatomical structure. Autopsy is used in pathology and forensic medicine to determine the cause of ...
was more often possible.


Notable contributors


Leonardo da Vinci (1452–1519)

Leonardo da Vinci Leonardo di ser Piero da Vinci (15 April 1452 - 2 May 1519) was an Italian polymath of the High Renaissance who was active as a painter, draughtsman, engineer, scientist, theorist, sculptor, and architect. While his fame initially rested o ...
made many contributions in the fields of science and technology. His research centered around his desire to learn more about how the human brain processes visual and sensory information and how that connects to the soul. Though his artwork was widely observed before, some of his original research was not made public until the 20th century. Some of da Vinci's research involved studying
vision Vision, Visions, or The Vision may refer to: Perception Optical perception * Visual perception, the sense of sight * Visual system, the physical mechanism of eyesight * Computer vision, a field dealing with how computers can be made to gain und ...
. He believed that visual information entered the body through the eye, then continued by sending nerve impulses through the
optic nerve In neuroanatomy, the optic nerve, also known as the second cranial nerve, cranial nerve II, or simply CN II, is a paired cranial nerve that transmits visual system, visual information from the retina to the brain. In humans, the optic nerve i ...
, and eventually reaching the soul. Da Vinci subscribed to the ancient notion that the soul was housed in the brain. He did research on the role of the
spinal cord The spinal cord is a long, thin, tubular structure made up of nervous tissue that extends from the medulla oblongata in the lower brainstem to the lumbar region of the vertebral column (backbone) of vertebrate animals. The center of the spinal c ...
in humans by studying frogs. He noted that as soon as the frogs medulla of the spine is broken, the frog would die. This led him to believe that the spine is the basis for the sense of touch, cause of movement, and the origin of nerves. As a result of his studies on the spinal cord, he also came to the conclusion that all peripheral nerves begin from the spinal cord. Da Vinci also did some research on the sense of smell. He is credited with being the first to define the olfactory nerve as one of the cranial nerves.
Leonardo da Vinci Leonardo di ser Piero da Vinci (15 April 1452 - 2 May 1519) was an Italian polymath of the High Renaissance who was active as a painter, draughtsman, engineer, scientist, theorist, sculptor, and architect. While his fame initially rested o ...
made his anatomical sketches based on observing and dissecting 30
cadaver A cadaver, often known as a corpse, is a Death, dead human body. Cadavers are used by medical students, physicians and other scientists to study anatomy, identify disease sites, determine causes of death, and provide tissue (biology), tissue to ...
s. His sketches were very detailed and included organs, muscles of superior extremity, the hand, and the skull. Leonardo was well known for his three-dimensional drawings. His anatomical drawings were not found until 380 years after his death.


Ambroise Paré (1510–1590)

Ambroise Paré Ambroise Paré (; – 20 December 1590) was a French barber surgeon who served in that role for kings Henry II, Francis II, Charles IX and Henry III. He is considered one of the fathers of surgery and modern forensic pathology and a pione ...
was a French surgeon, anatomist and an inventor of
surgical instruments A surgical instrument is a medical device for performing specific actions or carrying out desired effects during a surgery or operation, such as modifying biological tissue, or to provide access for viewing it. Over time, many different kinds of ...
. He was a military surgeon during the French campaigns in Italy of 1533–36. It was here that, having run out of boiling oil (which was the accepted way of treating firearm wounds), Paré turned to an ancient Roman remedy:
turpentine Turpentine (which is also called spirit of turpentine, oil of turpentine, terebenthine, terebenthene, terebinthine and, colloquially, turps) is a fluid obtainable by the distillation of resin harvested from living trees, mainly pines. Principall ...
, egg yolk and oil of roses. He applied it to the wounds and found that it relieved pain and sealed the wound effectively. Paré also introduced the ligatures of arteries; silk threads would be used to tie up the arteries of amputated limbs to try to stop the bleeding. As
antiseptic An antiseptic ( and ) is an antimicrobial substance or compound that is applied to living tissue to reduce the possibility of sepsis, infection, or putrefaction. Antiseptics are generally distinguished from ''antibiotics'' by the latter's abil ...
s had not yet been invented this method led to an increased fatality rate and was abandoned by medical professionals of the time. Additionally, Paré's contributions extended to the practice of surgical amputation and on the design and development of limb
prostheses In medicine, a prosthesis (: prostheses; from ), or a prosthetic implant, is an artificial device that replaces a missing body part, which may be lost through physical trauma, disease, or a condition present at birth (congenital disorder). Prosthe ...
. While caring for wounded soldiers, Paré recorded the pain endured by amputees, a phenomenon now recognized as phantom limb sensation. He believed that the phantom pain occurred in the brain and not in remnants of the limb.


Andreas Vesalius (1514–1564)

Andreas Vesalius Andries van Wezel (31 December 1514 – 15 October 1564), latinized as Andreas Vesalius (), was an anatomist and physician who wrote '' De Humani Corporis Fabrica Libri Septem'' (''On the fabric of the human body'' ''in seven books''), which is ...
was born in 1514 around midnight in
Brussels Brussels, officially the Brussels-Capital Region, (All text and all but one graphic show the English name as Brussels-Capital Region.) is a Communities, regions and language areas of Belgium#Regions, region of Belgium comprising #Municipalit ...
, then part of
Habsburg Netherlands Habsburg Netherlands were the parts of the Low Countries that were ruled by sovereigns of the Holy Roman Empire's House of Habsburg. This rule began in 1482 and ended for the Northern Netherlands in 1581 and for the Southern Netherlands in 1797. ...
, to a long lineage of doctors. His father was also an apothecary to
Charles V, Holy Roman Emperor Charles V (24 February 1500 – 21 September 1558) was Holy Roman Emperor and Archduke of Austria from 1519 to 1556, King of Spain (as Charles I) from 1516 to 1556, and Lord of the Netherlands as titular Duke of Burgundy (as Charles II) ...
. He would be born into the period of The Revival of Learning. He gained an interest in anatomy at a young age and began dissecting mice, moles, cats, and dogs. Vesalius picked up from the work of
Galen Aelius Galenus or Claudius Galenus (; September 129 – AD), often Anglicization, anglicized as Galen () or Galen of Pergamon, was a Ancient Rome, Roman and Greeks, Greek physician, surgeon, and Philosophy, philosopher. Considered to be one o ...
(129–c. 200 CE) which was based on the dissection of animals from pigs to apes.  The works of
Galen Aelius Galenus or Claudius Galenus (; September 129 – AD), often Anglicization, anglicized as Galen () or Galen of Pergamon, was a Ancient Rome, Roman and Greeks, Greek physician, surgeon, and Philosophy, philosopher. Considered to be one o ...
would be accepted until Vesalius. He would challenge the medieval views of human anatomy made by
Galen Aelius Galenus or Claudius Galenus (; September 129 – AD), often Anglicization, anglicized as Galen () or Galen of Pergamon, was a Ancient Rome, Roman and Greeks, Greek physician, surgeon, and Philosophy, philosopher. Considered to be one o ...
that had been taught for centuries. Vesalius paved the foundation of modern anatomy and most of his ideas are accepted today. Vesalius went to school in
Louvain Leuven (, , ), also called Louvain (, , ), is the capital and largest city of the province of Flemish Brabant in the Flemish Region of Belgium. It is located about east of Brussels. The municipality itself comprises the sub-municipalities of ...
and would enter the university there. His education was majorly taught by
Humanistic Humanism is a philosophical stance that emphasizes the individual and social potential, and agency of human beings, whom it considers the starting point for serious moral and philosophical inquiry. The meaning of the term "humanism" ha ...
teachers. Vesalius spent many hours in cemeteries in the burial ground of the Church of the Innocents in
Paris Paris () is the Capital city, capital and List of communes in France with over 20,000 inhabitants, largest city of France. With an estimated population of 2,048,472 residents in January 2025 in an area of more than , Paris is the List of ci ...
to study the bones that were misplaced from improper burial. Eventually, Vesalius and his friend stole one complete skeleton from the gallows; this was the first body Vesalius was able to dissect completely. He would go on to befriend judges and doctors, to gain access to human bodies of those who had just died for dissection. This would start rumors that connected Vesalius to
Vivisection Vivisection () is surgery conducted for experimental purposes on a living organism, typically animals with a central nervous system, to view living internal structure. The word is, more broadly, used as a pejorative catch-all term for Animal test ...
. Vesalius did want the most recent deceased cadavers and vivisection was frowned upon both then and currently. Vesalius eventually became a Doctor of Medicine at the age of 22. He noticed that many of his hands on experiences and findings with cadavers contradicted
Galen Aelius Galenus or Claudius Galenus (; September 129 – AD), often Anglicization, anglicized as Galen () or Galen of Pergamon, was a Ancient Rome, Roman and Greeks, Greek physician, surgeon, and Philosophy, philosopher. Considered to be one o ...
's teachings, to the point he would discarded all them. His students grew to be devoted followers and they would go grave robbing with Vesalius especially if a female was involved. He wrote around 14 books on his findings in anatomy, including his best known book ''
De humani corporis fabrica ''De Humani Corporis Fabrica Libri Septem'' (Latin, "On the Fabric of the Human Body in Seven Books") is a set of books on human anatomy written by Andreas Vesalius (1514–1564) and published in 1543. It was a major advance in the history of a ...
.'' It was revolutionary because of the accuracy and precision of his descriptions and images of organs and would refute
Galen Aelius Galenus or Claudius Galenus (; September 129 – AD), often Anglicization, anglicized as Galen () or Galen of Pergamon, was a Ancient Rome, Roman and Greeks, Greek physician, surgeon, and Philosophy, philosopher. Considered to be one o ...
's belief that human anatomy is closely related to apes. The book was a dedication to
Charles V, Holy Roman Emperor Charles V (24 February 1500 – 21 September 1558) was Holy Roman Emperor and Archduke of Austria from 1519 to 1556, King of Spain (as Charles I) from 1516 to 1556, and Lord of the Netherlands as titular Duke of Burgundy (as Charles II) ...
. Vesalius published ''
De humani corporis fabrica ''De Humani Corporis Fabrica Libri Septem'' (Latin, "On the Fabric of the Human Body in Seven Books") is a set of books on human anatomy written by Andreas Vesalius (1514–1564) and published in 1543. It was a major advance in the history of a ...
'' at the age of 28. With him being so young, it made his contributions harder to accept. ''De Fabrica'' was a milestone in medical science as it detailed many aspects of the human cadaver as well as presenting it in the form of art. Its imagery drew on new Renaissance methods in art. An example of his work is a picture of a dissected corpse hung by a rope through its eye sockets with the upper diaphragm on a wall behind the corpse. The book gave clear identification of the organs in the human body while also removing the aspects that he found flawed with
Galen Aelius Galenus or Claudius Galenus (; September 129 – AD), often Anglicization, anglicized as Galen () or Galen of Pergamon, was a Ancient Rome, Roman and Greeks, Greek physician, surgeon, and Philosophy, philosopher. Considered to be one o ...
's teachings. Vesalius was an important part of the Medical Renaissance. He is remembered as a critic of the inaccurate teachings of
Galen Aelius Galenus or Claudius Galenus (; September 129 – AD), often Anglicization, anglicized as Galen () or Galen of Pergamon, was a Ancient Rome, Roman and Greeks, Greek physician, surgeon, and Philosophy, philosopher. Considered to be one o ...
, and one of the founders of modern anatomy.


William Harvey (1578–1657)

William Harvey William Harvey (1 April 1578 – 3 June 1657) was an English physician who made influential contributions to anatomy and physiology. He was the first known physician to describe completely, and in detail, pulmonary and systemic circulation ...
was an English medical doctor-physicist, known for his contributions in heart and blood movement. William Harvey fully believed all medical knowledge should be universal, and he made this his works goal. Accomplished historians credit him for his boldness in his experimental work and his everlasting eagerness to implement modern practice. Although not the first to propose
pulmonary circulation The pulmonary circulation is a division of the circulatory system in all vertebrates. The circuit begins with deoxygenated blood returned from the body to the right atrium of the heart where it is pumped out from the right ventricle to the lun ...
(
Ibn al-Nafis ʿAlāʾ al-Dīn Abū al-Ḥasan ʿAlī ibn Abī Ḥazm al-Qarashī (Arabic: علاء الدين أبو الحسن عليّ بن أبي حزم القرشي ), known as Ibn al-Nafīs (Arabic: ابن النفيس), was an Arab polymath whose area ...
,
Michael Servetus Michael Servetus (; ; ; also known as ''Michel Servetus'', ''Miguel de Villanueva'', ''Revés'', or ''Michel de Villeneuve''; 29 September 1509 or 1511 – 27 October 1553) was a Spanish theologian, physician, cartographer, and Renaissance ...
and
Realdo Colombo Matteo Realdo Colombo (c. 1515 – 1559) was an Italian professor of anatomy and a surgeon at the University of Padua between 1544 and 1559. Early life and education Matteo Realdo Colombo or Realdus Columbus, was born in Cremona, Lombardy, the ...
preceded him), he is credited as the first person in the Western world to give quantitative arguments for the circulation of blood around the body. William Harvey's extensive work on the body's circulation can be found in the written work titles,
The Motu Cordis
.This work opens up with clear definitions of anatomy as well as types of anatomy which clearly outlined a universal meaning of these words for various Renaissance
physician A physician, medical practitioner (British English), medical doctor, or simply doctor is a health professional who practices medicine, which is concerned with promoting, maintaining or restoring health through the Medical education, study, Med ...
s. Anatomy, as defined by William Harvey is, "the faculty that by ocular inspection and dissection raspsthe uses and actions of the parts." In other words, to be able to identify the actions or roles each part of the body plays in the overall function of the body by dissection, followed by visual identification. These were the foundation for the further research on the heart and blood vessels.Kids Work! > History of Medicine
/ref>


Hieronymus Fabricius (1537–1619)

Hieronymus Fabricius Girolamo Fabrici d'Acquapendente, also known as Girolamo Fabrizio or Hieronymus Fabricius (; 20 May 1533 – 21 May 1619), was a pioneering anatomy, anatomist and surgeon known in medicine, medical science as "The Father of Embryology." Lif ...
was an anatomist and surgeon that prepared a human and animal anatomy atlas and these illustrations were used in his work, ''Tabulae Pictae.'' This work includes illustrations from many different artists and Fabricius is credited for providing a turning point in anatomical illustration. Fabricius' illustrations were of natural size and natural colors. After Fabricius' death, ''Tabulae Pictae'' disappeared and wasn't again discovered until 1909. Fabricus focused on the human brain and the fissures that are inside of the brain. In ''Tabulae Pictae'', he described the cerebral
fissure A fissure is a long, narrow crack opening along the surface of Earth. The term is derived from the Latin word , which means 'cleft' or 'crack'. Fissures emerge in Earth's crust, on ice sheets and glaciers, and on volcanoes. Ground fissure A ...
that separates the
temporal lobe The temporal lobe is one of the four major lobes of the cerebral cortex in the brain of mammals. The temporal lobe is located beneath the lateral fissure on both cerebral hemispheres of the mammalian brain. The temporal lobe is involved in pr ...
from the
frontal lobe The frontal lobe is the largest of the four major lobes of the brain in mammals, and is located at the front of each cerebral hemisphere (in front of the parietal lobe and the temporal lobe). It is parted from the parietal lobe by a Sulcus (neur ...
. He also studied veins and was the first to discover the valves inside of veins.


See also

* Fracastoro *
Learned medicine Learned medicine is the European medical tradition in the Early Modern period, when it experienced the tension between the texts derived from ancient Greek medicine, particularly by followers of the teachings attributed to Hippocrates and those of ...
*
Paracelsus Paracelsus (; ; 1493 – 24 September 1541), born Theophrastus von Hohenheim (full name Philippus Aureolus Theophrastus Bombastus von Hohenheim), was a Swiss physician, alchemist, lay theologian, and philosopher of the German Renaissance. H ...


References


Further reading

* *


External links


MSS 95, Item 15 Medical, alchemical, and craft materials recipes, 15th and 16th centuries. at OPenn
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Renaissance The Renaissance ( , ) is a Periodization, period of history and a European cultural movement covering the 15th and 16th centuries. It marked the transition from the Middle Ages to modernity and was characterized by an effort to revive and sur ...
Renaissance