Raphe ( ; from ;Liddell, H.G. & Scott, R. (1940). ''A Greek-English Lexicon. revised and augmented throughout by Sir Henry Stuart Jones. with the assistance of. Roderick McKenzie.'' Oxford: Clarendon Press. : raphae or raphes) has several different meanings in scientific terminology. In

botany Botany, also called plant science, is the branch of natural science and biology studying plants, especially Plant anatomy, their anatomy, Plant taxonomy, taxonomy, and Plant ecology, ecology. A botanist or plant scientist is a scientist who s ...

and

planktology Planktology is the study of plankton, various small drifting plants, animals and microorganisms that inhabit bodies of water. Planktology topics include primary production, energy flow and the carbon cycle. Plankton drive the "biological pump", ...

, it is commonly used when describing a seam or ridge on

diatom A diatom (Neo-Latin ''diatoma'') is any member of a large group comprising several Genus, genera of algae, specifically microalgae, found in the oceans, waterways and soils of the world. Living diatoms make up a significant portion of Earth's B ...

s or

seed In botany, a seed is a plant structure containing an embryo and stored nutrients in a protective coat called a ''testa''. More generally, the term "seed" means anything that can be Sowing, sown, which may include seed and husk or tuber. Seeds ...

s. In animal anatomy, it is used to describe a ridged union of continuous

biological tissue In biology, tissue is an assembly of similar cells and their extracellular matrix from the same embryonic origin that together carry out a specific function. Tissues occupy a biological organizational level between cells and a complete or ...

. There are several different significant anatomical raphes: * The

raphe nucleus The raphe nuclei (, "seam") are a moderate-size cluster of nuclei found in the brain stem. They have 5-HT1 receptors which are coupled with Gi/Go-protein-inhibiting adenyl cyclase. They function as autoreceptors in the brain and decrease the r ...

is a moderate-size cluster of nuclei found in the brain stem that releases

serotonin Serotonin (), also known as 5-hydroxytryptamine (5-HT), is a monoamine neurotransmitter with a wide range of functions in both the central nervous system (CNS) and also peripheral tissues. It is involved in mood, cognition, reward, learning, ...

to the rest of the brain. Selective serotonin reuptake inhibitor (SSRI) antidepressants are believed to act at these nuclei. * The buccal raphe, which is on the

cheek The cheeks () constitute the area of the face below the eyes and between the nose and the left or right ear. ''Buccal'' means relating to the cheek. In humans, the region is innervated by the buccal nerve. The area between the inside of th ...

and evidence of the fusion of the maxillary and mandibular processes * The lingual raphe on the

tongue The tongue is a Muscle, muscular organ (anatomy), organ in the mouth of a typical tetrapod. It manipulates food for chewing and swallowing as part of the digestive system, digestive process, and is the primary organ of taste. The tongue's upper s ...

. Obvious physical evidence of the lingual raphe includes the

frenulum A frenulum or frenum (: frenula or frena, from the Latin ''frēnulum'', "little bridle", the diminutive of ''frēnum'') is a small fold of tissue that secures the motion of a mobile organ in the body. In human anatomy Frenula on the human ...

(also called the frenum), or band of

mucous membrane A mucous membrane or mucosa is a membrane that lines various cavities in the body of an organism and covers the surface of internal organs. It consists of one or more layers of epithelial cells overlying a layer of loose connective tissue. It ...

that is visible under the tongue attaching it to the

floor of the mouth In human anatomy, the mouth is the first portion of the alimentary canal that receives food and produces saliva. The oral mucosa is the mucous membrane epithelium lining the inside of the mouth. In addition to its primary role as the beginning ...

. If this raphe is too tight at birth, movement of the tongue is restricted and the child is said to be "tongue tied". * The

palatine raphe The palatine raphe (also median palatine raphe) is a raphe of the oral cavity. It is a narrow, slight midline ridge extending anteroposteriorly across the palate, from the incisive papilla anteriorly to the palatine uvula posteriorly. Beneath t ...

on the roof of the mouth (or

palate The palate () is the roof of the mouth in humans and other mammals. It separates the oral cavity from the nasal cavity. A similar structure is found in crocodilians, but in most other tetrapods, the oral and nasal cavities are not truly sep ...

). Incomplete fusion of the palatine raphe results in a

congenital defect A birth defect is an abnormal condition that is present at birth, regardless of its cause. Birth defects may result in disabilities that may be physical, intellectual, or developmental. The disabilities can range from mild to severe. Birth de ...

known as

cleft palate A cleft lip contains an opening in the upper lip that may extend into the nose. The opening may be on one side, both sides, or in the middle. A cleft palate occurs when the palate (the roof of the mouth) contains an opening into the nose. The ...

. * The

pharyngeal raphe The pharyngeal raphe is a raphe that serves as the posterior attachment for several of the pharyngeal constrictors (thyropharyngeal part of the inferior pharyngeal constrictor muscle, middle pharyngeal constrictor muscle, superior pharyngeal cons ...

joins the left and right pharyngeal constrictors. * The

perineal raphe The perineal raphe is a visible line or ridge of tissue on the body that extends from the anus through the perineum to the scrotum (male) or the vulva (female). It is found in both males and females, arises from the fusion of the urogenital folds, ...

extends from the

anus In mammals, invertebrates and most fish, the anus (: anuses or ani; from Latin, 'ring' or 'circle') is the external body orifice at the ''exit'' end of the digestive tract (bowel), i.e. the opposite end from the mouth. Its function is to facil ...

, through the mid-line of the

scrotum In most terrestrial mammals, the scrotum (: scrotums or scrota; possibly from Latin ''scortum'', meaning "hide" or "skin") or scrotal sac is a part of the external male genitalia located at the base of the penis. It consists of a sac of skin ...

(scrotal raphe), and upwards through the ventral mid-line aspect of the

penis A penis (; : penises or penes) is a sex organ through which male and hermaphrodite animals expel semen during copulation (zoology), copulation, and through which male placental mammals and marsupials also Urination, urinate. The term ''pen ...

(

penile raphe The penile raphe is a visible line or ridge of tissue that runs on the ventral (urethral) side of the human penis beginning from the base of the shaft and ending in the prepuce between the penile frenulum. The line is typically darker than the ...

) in males. In females, it extends from the

, through the mid-line of the

perineum The perineum (: perineums or perinea) in placentalia, placental mammals is the space between the anus and the genitals. The human perineum is between the anus and scrotum in the male or between the anus and vulva in the female. The perineum is ...

to the posterior junction of the

labia majora In primates, and specifically in humans, the labia majora (: labium majus), also known as the outer lips or outer labia, are two prominent Anatomical terms of location, longitudinal skin folds that extend downward and backward from the mons pubis ...

. * The anococcygeal raphe, an alternative name for the

anococcygeal body The anococcygeal body (anococcygeal ligament or anococcygeal raphe) is a fibrous median raphe in the floor of the pelvis, which extends between the coccyx and the margin of the anus. It is composed of fibers of the levator ani muscle that unite wi ...

* The

iliococcygeal raphe The iliococcygeal raphe is a raphe Raphe ( ; from ;Liddell, H.G. & Scott, R. (1940). ''A Greek-English Lexicon. revised and augmented throughout by Sir Henry Stuart Jones. with the assistance of. Roderick McKenzie.'' Oxford: Clarendon Press. : ...

* The

pterygomandibular raphe The pterygomandibular raphe (pterygomandibular fold or pterygomandibular ligament) is a thin tendinous band of buccopharyngeal fascia. It is attached superiorly to the pterygoid hamulus of the medial pterygoid plate, and inferiorly to the poster ...

* The

lateral palpebral raphe The lateral palpebral raphe is a ligamentous band near the eye. Its existence is contentious, and many sources describe it as the continuation of nearby muscles. It is formed from the lateral ends of the orbicularis oculi muscle. It connects the ...

* The mylohyoid raphe

Teratology

teratology Teratology is the study of abnormalities of physiological development in organisms during their life span. It is a sub-discipline in medical genetics which focuses on the classification of congenital abnormalities in dysmorphology caused by ...

, a malformation or

congenital disorder A birth defect is an abnormal condition that is present at childbirth, birth, regardless of its cause. Birth defects may result in disability, disabilities that may be physical disability, physical, intellectual disability, intellectual, or dev ...

involving a raphe, such as

spina bifida Spina bifida (SB; ; Latin for 'split spine') is a birth defect in which there is incomplete closing of the vertebral column, spine and the meninges, membranes around the spinal cord during embryonic development, early development in pregnancy. T ...

, is known as a dysraphism.

References

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