Raf-like Ras-binding domain is an evolutionary conserved

protein domain In molecular biology, a protein domain is a region of a protein's polypeptide chain that is self-stabilizing and that folds independently from the rest. Each domain forms a compact folded three-dimensional structure. Many proteins consist o ...

. This is the Ras-binding domain found in proteins related to Ras.

Examples

Human proteins containing this domain include: *

ARAF Serine/threonine-protein kinase A-Raf or simply A-Raf is an enzyme that in humans is encoded by the ''ARAF'' gene. A-Raf is a member of the Raf kinase family of serine/threonine-specific protein kinases. Compared to the other members of this ...

* BRAF *

RAF1 RAF proto-oncogene serine/threonine-protein kinase, also known as proto-oncogene c-RAF or simply c-Raf or even Raf-1, is an enzyme that in humans is encoded by the ''RAF1'' gene. The c-Raf protein is part of the ERK1/2 pathway as a MAP kinase ...

RGS12 Regulator of G-protein signaling 12 is a protein that in humans is encoded by the ''RGS12'' gene. This gene encodes a member of the 'regulator of G protein signaling' (RGS) gene family. The encoded protein may function as a guanosine triphosphatas ...

RGS14 Regulator of G-protein signaling 14 (RGS14) is a protein that in humans is encoded by the ''RGS14'' gene. Function RGS14 is a member of the regulator of G protein signalling family. This protein contains one RGS domain, two Raf-like Ras-bind ...

TIAM1 T-cell lymphoma invasion and metastasis-inducing protein 1 is a protein that in humans is encoded by the ''TIAM1'' gene. Structure TIAM1 is tightly associate with BAIAP2 as a subunit. It contains one DH (DBL-homology) domain, one PDZ domain, ...

References

Protein domains {{protein-stub