Rab GTPase-binding effector protein 1 is an
enzyme
Enzymes () are proteins that act as biological catalysts by accelerating chemical reactions. The molecules upon which enzymes may act are called substrate (chemistry), substrates, and the enzyme converts the substrates into different molecule ...
that in humans is encoded by the ''RABEP1''
gene
In biology, the word gene (from , ; "... Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a b ...
.
It belongs to
rabaptin
Rabaptin is a key protein involved in regeneration of injured axons.
Regeneration of injured axons at neuromuscular junctions is regulated by extra-cellular protein factors that promote neurite outgrowth. A novel neurite outgrowth factor from chi ...
protein family.
Interactions
RABEP1 has been shown to
interact
Advocates for Informed Choice, dba interACT or interACT Advocates for Intersex Youth, is a 501(c)(3) nonprofit organization using innovative strategies to advocate for the legal and human rights of children with intersex traits. The organizat ...
with:
*
AP1G1
AP-1 complex subunit gamma-1 is a protein that in humans is encoded by the ''AP1G1'' gene.
Function
Adaptins are important components of clathrin-coated vesicles transporting ligand-receptor complexes from the plasma membrane or from the trans ...
,
GGA1
ADP-ribosylation factor-binding protein GGA1 is a protein that in humans is encoded by the ''GGA1'' gene.
This gene encodes a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) protein family. Members of this family ar ...
,[
* ]GGA2
ADP-ribosylation factor-binding protein GGA2 is a protein that in humans is encoded by the ''GGA2'' gene.
Function
This gene encodes a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) family. This family includes ...
,RAB4A
Ras-related protein Rab-4A is a protein that in humans is encoded by the ''RAB4A'' gene.
Interactions
RAB4A has been shown to interact with:
* CD2AP,
* KIF3B,
* RAB11FIP1,
* RABEP1, and
* STX4
Syntaxin-4 is a protein that in humans is e ...
,RAB5A
Ras-related protein Rab-5A is a protein that in humans is encoded by the ''RAB5A'' gene.
Function
RAB5A localizes to early endosomes where it is involved in the recruitment of RAB7A and the maturation of these compartments to late endosomes. I ...
.
References
Further reading
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