RIP kinases (receptor-interacting protein kinases) are a class of

serine/threonine protein kinase A serine/threonine protein kinase () is a kinase enzyme, in particular a protein kinase, that phosphorylates the OH group of the amino-acid residues serine or threonine, which have similar side chains. At least 350 of the 500+ human pro ...

s. In humans, five different RIP kinases are known: *

RIPK1 Receptor-interacting serine/threonine-protein kinase 1 (RIPK1) functions in a variety of cellular pathways related to both cell survival and death. In terms of cell death, RIPK1 plays a role in apoptosis, necroptosis, and PANoptosis Some of th ...

RIPK2 Receptor-interacting serine/threonine-protein kinase 2 is an enzyme that in humans is encoded by the ''RIPK2'' gene. This gene encodes a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. The encoded pro ...

RIPK3 Receptor-interacting serine/threonine-protein kinase 3 is an enzyme that is encoded by the ''RIPK3'' gene in humans. The product of this gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. It c ...

RIPK4 Receptor-interacting serine/threonine-protein kinase 4 is an enzyme that in humans is encoded by the ''RIPK4'' gene. The protein encoded by this gene is a serine/threonine protein kinase that interacts with protein kinase C-delta. The encoded pr ...

* RIPK5

Further reading