Regulator of G-protein signaling 5 is a
protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, respon ...
that in humans is encoded by the ''RGS5''
gene
In biology, the word gene (from , ; "... Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a b ...
.
The regulator of G protein signaling (RGS) proteins are signal transduction molecules that have structural homology to SST2 of Saccharomyces cerevisiae and EGL-10 of Caenorhabditis elegans. Multiple genes homologous to SST2 are present in higher eukaryotes. RGS proteins are involved in the regulation of heterotrimeric G proteins by acting as GTPase activators.
Interactions
RGS5 has been shown to
interact with
GNAO1,
[ and ]GNAI3
Guanine nucleotide-binding protein G(k) subunit alpha is a protein that in humans is encoded by the ''GNAI3'' gene.
Interactions
GNAI3 has been shown to interact with:
* RGS10
* RGS12,
* RGS14,
* RGS16,
* RGS18,
* RGS19,
* RGS5,
* ...
.[
]
References
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