Transcription factor RFX3 is a
protein that in humans is encoded by the ''RFX3''
gene.
This gene is a member of the regulatory factor X gene family, which encodes
transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X1, X2, X4, and X5. It is a
transcriptional activator that can bind
DNA as a monomer or as a heterodimer with other RFX family members. Two transcript variants encoding different
isoforms have been described for this gene, and at least one of the variants utilizes alternative
polyadenylation
Polyadenylation is the addition of a poly(A) tail to an RNA transcript, typically a messenger RNA (mRNA). The poly(A) tail consists of multiple adenosine monophosphates; in other words, it is a stretch of RNA that has only adenine bases. In euk ...
signals.
References
Further reading
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Transcription factors
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