RB-3007 is an orally active analogue of
RB-101
RB-101 is a drug that acts as an enkephalinase inhibitor, which is used in scientific research.
RB-101 is a prodrug which acts by splitting at the disulfide bond once inside the brain, to form two selective enzyme inhibitors and blocking both ...
. It acts as an
enkephalinase inhibitor
An enkephalinase inhibitor is a type of enzyme inhibitor which inhibits one or more members of the enkephalinase class of enzymes that break down the endogenous enkephalin opioid peptides. Examples include racecadotril, ubenimex (bestatin), RB-1 ...
, which is used in scientific research.
See also
*
RB-101
RB-101 is a drug that acts as an enkephalinase inhibitor, which is used in scientific research.
RB-101 is a prodrug which acts by splitting at the disulfide bond once inside the brain, to form two selective enzyme inhibitors and blocking both ...
- enkephalinase inhibitor that produces analgesia without
respiratory depression
Hypoventilation (also known as respiratory depression) occurs when ventilation is inadequate (''hypo'' meaning "below") to perform needed respiratory gas exchange. By definition it causes an increased concentration of carbon dioxide (hypercapni ...
*
D/DL-Phenylalanine - D-phenylalanine blockage of
enkephalin
An enkephalin is a pentapeptide involved in regulating nociception (pain sensation) in the body. The enkephalins are termed endogenous ligands, as they are internally derived (and therefore endogenous) and bind as ligands to the body's opioid ...
degradation may be responsible for the reputed
analgesic effect of DL-Phenylalanine
*
Racecadotril - an
antidiarrheal drug which acts as a peripheral enkephalinase inhibitor
*
Ecadotril - a neutral
endopeptidase inhibitor
References
{{reflist
Enkephalinase inhibitors
Organophosphates
Biphenyls
Benzyl esters
Acetyl compounds