Ral guanine nucleotide dissociation stimulator is a
protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, respon ...
that is encoded by the ''RALGDS''
gene
In biology, the word gene (from , ; "... Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a b ...
in humans.
Interactions
RALGDS has been shown to
interact
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with:
*
Arrestin beta 1
Arrestin, beta 1, also known as ARRB1, is a protein which in humans is encoded by the ''ARRB1'' gene.
Function
Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G protein-coupled ...
,
[
* ]Arrestin beta 2
Beta-arrestin-2, also known as arrestin beta-2, is an intracellular protein that in humans is encoded by the ''ARRB2'' gene.
Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G prot ...
,
* HRAS
GTPase HRas, from "Harvey Rat sarcoma virus", also known as transforming protein p21 is an enzyme that in humans is encoded by the gene. The ''HRAS'' gene is located on the short (p) arm of chromosome 11 at position 15.5, from base pair 522,241 ...
,
* KRAS
''KRAS'' ( Kirsten rat sarcoma virus) is a gene that provides instructions for making a protein called K-Ras, a part of the RAS/MAPK pathway. The protein relays signals from outside the cell to the cell's nucleus. These signals instruct the cel ...
,
* MRAS,
* RAP1A
Ras-related protein Rap-1A is a protein that in humans is encoded by the ''RAP1A'' gene.
Function
The product of this gene belongs to the family of Ras-related proteins. These proteins share approximately 50% amino acid identity with the clas ...
,[
* RAP2A,]
* RAPGEF2
Rap guanine nucleotide exchange factor 2 is a protein that in humans is encoded by the ''RAPGEF2'' gene.
RAPGEF2 is a cyclic AMP binding protein.
Function
Members of the RAS subfamily of GTPases function in signal transduction as GTP/GDP-regul ...
,[ and
* RRAS.]
References
Further reading
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{{PDB Gallery, geneid=5900