asR3 is an
archeal small RNA
Small RNA (sRNA) are polymeric RNA molecules that are less than 200 nucleotides in length, and are usually non-coding
Non-coding DNA (ncDNA) sequences are components of an organism's DNA that do not encode protein sequences. Some non-coding DNA ...
identified in seven ''
Pyrobaculum
''Pyrobaculum'' is a genus of the Thermoproteaceae.
Description and significance
As its Latin name ''Pyrobaculum'' (the "fire stick") suggests, the archaeon is rod-shaped and isolated from locations with high temperatures. It is Gram-negative ...
'' species. The genus-specific nature can indicate this could be recent, stable adaptation.
asR3 binds to the 3′-end of the ''tpi'' gene (
triose-phosphate-isomerse).
The tpi mRNA has a conserved structural element located close to the stop codon. Binding of the asR3 may be able to compete against the formation of the tpi element structure and this may modulate the function of this highly conserved element.
References
See also
Other archaeal sRNAs:
*
Archaeal H/ACA sRNA
*
Methanosarcina sRNA162
Non-coding RNA
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