Purine Imidazole-ring Cyclase
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The enzyme purine imidazole-ring cyclase (EC 4.3.2.4)
catalyzes Catalysis () is the increase in rate of a chemical reaction due to an added substance known as a catalyst (). Catalysts are not consumed by the reaction and remain unchanged after it. If the reaction is rapid and the catalyst recycles quick ...
the
chemical reaction A chemical reaction is a process that leads to the chemistry, chemical transformation of one set of chemical substances to another. When chemical reactions occur, the atoms are rearranged and the reaction is accompanied by an Gibbs free energy, ...
:DNA 4,6-diamino-5-formamidopyrimidine \rightleftharpoons DNA adenine + H2O This enzyme belongs to the family of
lyase In biochemistry, a lyase is an enzyme that catalyzes the breaking (an elimination reaction) of various chemical bonds by means other than hydrolysis (a substitution reaction) and oxidation Redox ( , , reduction–oxidation or oxidatio ...
s, specifically amidine lyases. The
systematic name A systematic name is a name given in a systematic way to one unique group, organism, object or chemical substance, out of a specific population or collection. Systematic names are usually part of a nomenclature. A semisystematic name or semitrivi ...
of this enzyme class is DNA-4,6-diamino-5-formamidopyrimidine C8-N9-lyase (cyclizing DNA-adenine-forming). Other names in common use include DNA-4,6-diamino-5-formamidopyrimidine 8-''C'',9-''N''-lyase (cyclizing), DNA-4,6-diamino-5-formamidopyrimidine 8-''C'',9-''N''-lyase (cyclizing, DNA-adenine-forming).


References

* EC 4.3.2 Enzymes of unknown structure {{enzyme-stub