Punicalin is an ellagitannin. It can be found in ''

Punica granatum The pomegranate (''Punica granatum'') is a fruit-bearing deciduous shrub in the family Lythraceae, subfamily Punicoideae, that grows between tall. The pomegranate was originally described throughout the Mediterranean region. It was introdu ...

'' (pomegranate) or in the leaves of ''

Terminalia catappa ''Terminalia catappa'' is a large tropical tree in the leadwood tree family, Combretaceae, native to Asia, Australia, the Pacific, Madagascar and Seychelles. Common names in English include country almond, Indian almond, Malabar almond, sea almon ...

'', a plant used to treat

dermatitis Dermatitis is inflammation of the skin, typically characterized by itchiness, redness and a rash. In cases of short duration, there may be small blisters, while in long-term cases the skin may become thickened. The area of skin involved can ...

and

hepatitis Hepatitis is inflammation of the liver parenchyma, liver tissue. Some people or animals with hepatitis have no symptoms, whereas others develop yellow discoloration of the skin and whites of the eyes (jaundice), Anorexia (symptom), poor appetite ...

. It is also reported in '' Combretum glutinosum'', all three species being

Myrtales The Myrtales are an order of flowering plants placed as a sister to the eurosids II clade as of the publishing of the ''Eucalyptus grandis'' genome in June 2014. The APG III system of classification for angiosperms still places it within the eu ...

, the two last being

Combretaceae The Combretaceae, often called the white mangrove family, are a family of flowering plants in the order Myrtales. The family includes about 530 species of trees, shrubs, and lianas in ca 10 genera. The family includes the leadwood tree, '' Combr ...

. It is a highly active

carbonic anhydrase inhibitor Carbonic anhydrase inhibitors are a class of pharmaceuticals that suppress the activity of carbonic anhydrase. Their clinical use has been established as anti-glaucoma agents, diuretics, antiepileptics, in the management of mountain sickness, g ...

Chemistry

The molecule contains a gallagic acid component linked to a

glucose Glucose is a simple sugar with the molecular formula . Glucose is overall the most abundant monosaccharide, a subcategory of carbohydrates. Glucose is mainly made by plants and most algae during photosynthesis from water and carbon dioxide, usi ...

References

Pomegranate ellagitannins Carbonic anhydrase inhibitors {{aromatic-stub