''Psychrobacter cryohalolentis'' is a

Gram-negative Gram-negative bacteria are bacteria that, unlike gram-positive bacteria, do not retain the crystal violet stain used in the Gram staining method of bacterial differentiation. Their defining characteristic is that their cell envelope consists ...

, nonmotile species of bacteria. It was first isolated from Siberian

permafrost Permafrost () is soil or underwater sediment which continuously remains below for two years or more; the oldest permafrost has been continuously frozen for around 700,000 years. Whilst the shallowest permafrost has a vertical extent of below ...

. Its type strain is K5^T (=DSM 17306^T =VKM B-2378^T). Hypoacylated

lipopolysaccharide Lipopolysaccharide (LPS), now more commonly known as endotoxin, is a collective term for components of the outermost membrane of the cell envelope of gram-negative bacteria, such as '' E. coli'' and ''Salmonella'' with a common structural archit ...

(LPS) from ''P. cryohalolentis'' induces moderate

TLR4 Toll-like receptor 4 (TLR4), also designated as CD284 (cluster of differentiation 284), is a key activator of the innate immune response and plays a central role in the fight against bacterial infections. TLR4 is a transmembrane protein of approx ...

-mediated inflammatory response in

macrophages Macrophages (; abbreviated MPhi, φ, MΦ or MP) are a type of white blood cell of the innate immune system that engulf and digest pathogens, such as cancer cells, microbes, cellular debris and foreign substances, which do not have proteins that ...

and such LPS bioactivity may potentially result in the failure of local and systemic bacterial clearance in patients.

References

External links

LPSN
*
Type strain of ''Psychrobacter cryohalolentis'' at Bac''Dive'' - the Bacterial Diversity Metadatabase
Moraxellaceae Bacteria described in 2007 {{Pseudomonadales-stub

References

Further reading

External links