Prospero Pubblicola Santacroce (24 September 1514 – 2 October 1589) was an

Italian Italian(s) may refer to: * Anything of, from, or related to the people of Italy over the centuries ** Italians, a Romance ethnic group related to or simply a citizen of the Italian Republic or Italian Kingdom ** Italian language, a Romance languag ...

Roman Catholic The Catholic Church (), also known as the Roman Catholic Church, is the largest Christian church, with 1.27 to 1.41 billion baptized Catholics worldwide as of 2025. It is among the world's oldest and largest international institut ...

bishop A bishop is an ordained member of the clergy who is entrusted with a position of Episcopal polity, authority and oversight in a religious institution. In Christianity, bishops are normally responsible for the governance and administration of di ...

and

cardinal Cardinal or The Cardinal most commonly refers to * Cardinalidae, a family of North and South American birds **''Cardinalis'', genus of three species in the family Cardinalidae ***Northern cardinal, ''Cardinalis cardinalis'', the common cardinal of ...

. He was active in Church affairs as a diplomat and prelate in Rome.

Biography

Santacroce was born in

Rome Rome (Italian language, Italian and , ) is the capital city and most populated (municipality) of Italy. It is also the administrative centre of the Lazio Regions of Italy, region and of the Metropolitan City of Rome. A special named with 2, ...

on September 24, 1514, the son of Tarquinio Santacroce and Ersilia de' Massimi. He was the uncle of Cardinal

Antonio Santacroce Antonio is a masculine given name of Etruscan origin deriving from the root name Antonius. It is a common name among Romance language–speaking populations as well as the Balkans and Lusophone Africa. It has been among the top 400 most popular ...

. He received a

doctorate A doctorate (from Latin ''doctor'', meaning "teacher") or doctoral degree is a postgraduate academic degree awarded by universities and some other educational institutions, derived from the ancient formalism '' licentia docendi'' ("licence to teach ...

from the

University of Padua The University of Padua (, UNIPD) is an Italian public research university in Padua, Italy. It was founded in 1222 by a group of students and teachers from the University of Bologna, who previously settled in Vicenza; thus, it is the second-oldest ...

. He then returned to Rome, becoming a consistorial lawyer in 1537. In 1538, he became the

auditor An auditor is a person or a firm appointed by a company to execute an audit.Practical Auditing, Kul Narsingh Shrestha, 2012, Nabin Prakashan, Nepal To act as an auditor, a person should be certified by the regulatory authority of accounting an ...

of Fabio Mignanelli, who was then

nuncio An apostolic nuncio (; also known as a papal nuncio or simply as a nuncio) is an ecclesiastical diplomat, serving as an envoy or a permanent diplomatic representative of the Holy See to a state or to an international organization. A nuncio is ...

before

Charles V, Holy Roman Emperor Charles V (24 February 1500 – 21 September 1558) was Holy Roman Emperor and Archduke of Austria from 1519 to 1556, King of Spain (as Charles I) from 1516 to 1556, and Lord of the Netherlands as titular Duke of Burgundy (as Charles II) ...

. He later became a

referendary Referendary is the English form of a number of administrative positions, of various rank, in chanceries and other official organizations in Europe. Pre-modern history The office of ' (plural: ', from the Latin ', "I inform") existed at the Byza ...

of the

Apostolic Signatura The Supreme Tribunal of the Apostolic Signatura () is the highest judicial authority in the Catholic Church (apart from the pope himself, who as supreme ecclesiastical judge is the final point of appeal on any ecclesiastical matter). In addition, ...

. In 1543, he became an auditor of the

Roman Rota The Roman Rota, formally the Apostolic Tribunal of the Roman Rota (), and anciently the Apostolic Court of Audience, is the highest appellate tribunal of the Catholic Church, with respect to both Latin Church members and the Eastern Catholic m ...

. The next year he was an auditor of Cardinal Alessandro Farnese, who was then

papal legate 300px, A woodcut showing Henry II of England greeting the Pope's legate. A papal legate or apostolic legate (from the ancient Roman title '' legatus'') is a personal representative of the Pope to foreign nations, to some other part of the Catho ...

''a latere'' in the

Holy Roman Empire The Holy Roman Empire, also known as the Holy Roman Empire of the German Nation after 1512, was a polity in Central and Western Europe, usually headed by the Holy Roman Emperor. It developed in the Early Middle Ages, and lasted for a millennium ...

. He accompanied the cardinal to the

Diet of Worms The Diet of Worms of 1521 ( ) was an Imperial Diet (Holy Roman Empire), imperial diet (a formal deliberative assembly) of the Holy Roman Empire called by Emperor Charles V, Holy Roman Emperor, Charles V and conducted in the Imperial Free City o ...

in May 1545. On March 22, 1548, he was elected Bishop of

Cisamus Detail of a Roman mosaic found at Cisamus Statue of emperor Hadrian from Cisamus Cisamus or Kisamos () was town of ancient Crete. It appears as one of two towns of the name in the Peutinger Table 32 M.P. to the west of Cydonia. The name appear ...

. From April 5, 1548 until April 25, 1550, he was nuncio before Ferdinand, King of the Romans; during this time, he participated in the Diet of

Prague Prague ( ; ) is the capital and List of cities and towns in the Czech Republic, largest city of the Czech Republic and the historical capital of Bohemia. Prague, located on the Vltava River, has a population of about 1.4 million, while its P ...

, where he argued with the

Hussite file:Hussitenkriege.tif, upright=1.2, Battle between Hussites (left) and Crusades#Campaigns against heretics and schismatics, Catholic crusaders in the 15th century file:The Bohemian Realm during the Hussite Wars.png, upright=1.2, The Lands of the ...

s. He was nuncio to the

Kingdom of France The Kingdom of France is the historiographical name or umbrella term given to various political entities of France in the Middle Ages, medieval and Early modern France, early modern period. It was one of the most powerful states in Europe from th ...

from July 15, 1552 until May 23, 1554. He became governor of

Bologna Bologna ( , , ; ; ) is the capital and largest city of the Emilia-Romagna region in northern Italy. It is the List of cities in Italy, seventh most populous city in Italy, with about 400,000 inhabitants and 150 different nationalities. Its M ...

on April 2, 1560. He was nuncio extraordinary in

Spain Spain, or the Kingdom of Spain, is a country in Southern Europe, Southern and Western Europe with territories in North Africa. Featuring the Punta de Tarifa, southernmost point of continental Europe, it is the largest country in Southern Eur ...

in 1560, and nuncio to the

Kingdom of Portugal The Kingdom of Portugal was a Portuguese monarchy, monarchy in the western Iberian Peninsula and the predecessor of the modern Portuguese Republic. Existing to various extents between 1139 and 1910, it was also known as the Kingdom of Portugal a ...

July 6, 1560 until May 10, 1561. During his time in Portugal, he became the first European to cultivate

tobacco Tobacco is the common name of several plants in the genus '' Nicotiana'' of the family Solanaceae, and the general term for any product prepared from the cured leaves of these plants. More than 70 species of tobacco are known, but the ...

for the purpose of

tobacco smoking Tobacco smoking is the practice of burning tobacco and ingesting the resulting smoke. The smoke may be inhaled, as is done with cigarettes, or released from the mouth, as is generally done with pipes and cigars. The practice is believed to hav ...

; as a result, tobacco's original name in the

Italian language Italian (, , or , ) is a Romance language of the Indo-European language family. It evolved from the colloquial Latin of the Roman Empire. Italian is the least divergent language from Latin, together with Sardinian language, Sardinian. It is ...

was ''erba Santacroce''. From 1561 to 1565, he was again nuncio to the Kingdom of France.

Pope Pius IV Pope Pius IV (; 31 March 1499 – 9 December 1565), born Giovanni Angelo Medici, was head of the Catholic Church and ruler of the Papal States from 25 December 1559 to his death, in December 1565. Born in Milan, his family considered itself a b ...

made him a

cardinal priest A cardinal is a senior member of the clergy of the Catholic Church. As titular members of the clergy of the Diocese of Rome, they serve as advisors to the pope, who is the bishop of Rome and the visible head of the worldwide Catholic Church. Ca ...

in the

consistory Consistory is the anglicized form of the consistorium, a council of the closest advisors of the Roman emperors. It can also refer to: *A papal consistory, a formal meeting of the Sacred College of Cardinals of the Roman Catholic Church *Consistor ...

of March 12, 1565. He did not, however, participate in the papal conclave of 1565-66 that elected

Pope Pius V Pope Pius V, OP (; 17 January 1504 – 1 May 1572), born Antonio Ghislieri (and from 1518 called Michele Ghislieri), was head of the Catholic Church and ruler of the Papal States from 7 January 1566 to his death, in May 1572. He was an ...

. He received the

red hat Red Hat, Inc. (formerly Red Hat Software, Inc.) is an American software company that provides open source software products to enterprises and is a subsidiary of IBM. Founded in 1993, Red Hat has its corporate headquarters in Raleigh, North ...

and the

titular church In the Catholic Church, a titular church () is a Churches in Rome, church in Rome that is assigned to a member of the Holy orders in the Catholic Church, clergy who is created a Cardinal (Catholic Church), cardinal. These are Catholic churches in ...

of Saint Jerome of the Croats on February 8, 1566. On June 17, 1566, he became administrator of the Diocese of Arles, while retaining the government of Cisamus. He opted for the titular church of

Santa Maria degli Angeli e dei Martiri The Basilica of St. Mary of the Angels and of the Martyrs (, ) is a Catholic titular minor basilica and former Carthusian conventual church in Rome, Italy, constructed in the ruined '' frigidarium'' and '' tepidarium'' of the Roman Baths of ...

on April 12, 1570. He participated in the papal conclave of 1572 that elected

Pope Gregory XIII Pope Gregory XIII (, , born Ugo Boncompagni; 7 January 1502 – 10 April 1585) was head of the Catholic Church and ruler of the Papal States from 13 May 1572 to his death in April 1585. He is best known for commissioning and being the namesake ...

. He resigned the government of Cisamus sometime before December 10, 1572 and of Arles sometime before March 15, 1574. On May 5, 1574, he opted for the titular church of

Sant'Adriano al Foro Sant'Adriano al Foro was a church in Rome, formerly in the Curia Julia in the ''Forum Romanum'' and a cardinal-deaconry (a titular church for a Cardinal-deacon). The church The Church of Sant'Adriano al Foro (Italian for St. (H)Adrian at ...

(a deaconry raised to the status of title ''pro illa vice''). He was Camerlengo of the Sacred College of Cardinals from January 9, 1581 to January 8, 1582. On March 4, 1583, he opted for the titular church of

San Clemente San Clemente (; Spanish for " St. Clement" ) is a coastal city in southern Orange County, California, United States. It was named in 1925 after the Spanish colonial island (which was named after a Pope from the first century). Located in the O ...

. He was a participant in the papal conclave of 1585 that elected

Pope Sixtus V Pope Sixtus V (; 13 December 1521 – 27 August 1590), born Felice Piergentile, was head of the Catholic Church and ruler of the Papal States from 24 April 1585 to his death, in August 1590. As a youth, he joined the Franciscan order, where h ...

. On March 2, 1589, he opted for the order of

cardinal bishop A cardinal is a senior member of the clergy of the Catholic Church. As titular members of the clergy of the Diocese of Rome, they serve as advisors to the pope, who is the bishop of Rome and the visible head of the worldwide Catholic Church. C ...

s, receiving the suburbicarian see of Albano. He died in Rome on October 2, 1589. He was buried in the

Basilica di Santa Maria Maggiore Santa Maria Maggiore (), also known as the Basilica of Saint Mary Major or the Basilica of Saint Mary the Great, is one of the four major papal basilicas and one of the Seven Pilgrim Churches of Rome. The largest Marian church in Rome, it is ...

. His remains were later transferred to Santa Maria in Publicolis. --See also

* Smoking in Italy

References

{{DEFAULTSORT:Santacroce, Prospero 1514 births 1589 deaths 16th-century Italian cardinals Apostolic nuncios to France