Prospect Hill virus is a single-stranded,
negative-sense
In molecular biology and genetics, the sense of a nucleic acid molecule, particularly of a strand of DNA or RNA, refers to the nature of the roles of the strand and its complement in specifying a sequence of amino acids. Depending on the context, ...
Hantaan-like
zoonotic
A zoonosis (; plural zoonoses) or zoonotic disease is an infectious disease of humans caused by a pathogen (an infectious agent, such as a virus, bacterium, parasite, fungi, or prion) that can jump from a non-human vertebrate to a human. When h ...
RNA virus
An RNA virus is a virus characterized by a ribonucleic acid (RNA) based genome. The genome can be single-stranded RNA (ssRNA) or double-stranded (Double-stranded RNA, dsRNA). Notable human diseases caused by RNA viruses include influenza, SARS, ...
isolated from
meadow vole
The eastern meadow vole (''Microtus pennsylvanicus''), sometimes called the field mouse or meadow mouse, is a North American vole found in eastern Canada and the United States. Its range extends farther south along the Atlantic coast.
The weste ...
s and
microtine
The Arvicolinae are a subfamily of rodents that includes the voles, lemmings, and muskrats. They are most closely related to the other subfamilies in the Cricetidae (comprising the hamsters and New World rats and mice). Some authorities place t ...
and other
cricetid
The Cricetidae are a family of rodents in the large and complex superfamily Muroidea. It includes true hamsters, voles, lemmings, muskrats, and New World rats and mice. At over 870 species, it is either the largest or second-largest family of mam ...
rodents in the United States.
[ It has a widespread distribution in Pennsylvania, Maryland, West Virginia, Minnesota and California. The overall risk of infection in humans is low. It was first isolated from a meadow vole found in Prospect Hill, Maryland for which it is named.][Yanagihara R, Daum CA, Lee PW, Baek LJ, Amyx HL, Gajdusek DC, Gibbs CJ Jr.Serological survey of Prospect Hill virus infection in indigenous wild rodents in the USA.Trans R Soc Trop Med Hyg. 1987;81(1):42–5.]
See also
* Isla Vista virus
''Orthohantavirus'' is a genus of viruses that includes all hantaviruses (family ''Hantaviridae'') that cause disease in humans. Orthohantaviruses, hereafter referred to as hantaviruses, are naturally found primarily in rodents. In general, each ...
* Hantaan River virus
Hantaan virus (HTNV) is the main cause of hemorrhagic fever with renal syndrome (HFRS) in East Asia. Hantaan virus is transmitted by the striped field mouse (''Apodemus agrarius'') In its natural reservoir, HTNV causes a persistent, asymptomati ...
* Bloodland Lake virus
Bloodland Lake virus (BLLV) is a single-stranded, negative-sense RNA virus of New World ''Orthohantavirus'' first isolated in a Prairie vole (''Microtus ochrogaster'') near Bloodland Lake, Fort Leonard Wood, Pulaski County, Missouri in 1994. BLL ...
References
External links
Sloan Science and Film / Short Films / Muerto Canyon
by Jen Peel 29 minutes
by Brian Hjelle, M.D., Department of Pathology, School of Medicine, University of New Mexico
Virus Pathogen Database and Analysis Resource (ViPR): Bunyaviridae
Viral diseases
Hantaviridae
Rodent-carried diseases
{{Virus-stub}