The pronephric duct is the predecessor of the

mesonephric duct The mesonephric duct, also known as the Wolffian duct, archinephric duct, Leydig's duct or nephric duct, is a paired organ that develops in the early stages of embryonic development in humans and other mammals. It is an important structure that pl ...

(Wolffian duct).

Development

The development of the pronephric duct is a part of the

development of the urinary system The development of the urinary system begins during prenatal development, and relates to the development of the urogenital system – both the organs of the urinary system and the sex organs of the reproductive system. The development continues as ...

, and the

development of the reproductive system The development of the reproductive system is the part of embryonic growth that results in the sex organs and contributes to sexual differentiation. Due to its large overlap with development of the urinary system, the two systems are typicall ...

. In the outer part of the

intermediate mesoderm Intermediate mesoderm or intermediate mesenchyme is a narrow section of the mesoderm (one of the three primary germ layers) located between the paraxial mesoderm and the lateral plate of the developing embryo. The intermediate mesoderm develops in ...

, immediately under the ectoderm, in the region from the fifth

cervical segment The spinal cord is a long, thin, tubular structure made up of nervous tissue that extends from the medulla oblongata in the lower brainstem to the lumbar region of the vertebral column (backbone) of vertebrate animals. The center of the spinal c ...

to the third

thoracic segment The spinal cord is a long, thin, tubular structure made up of nervous tissue that extends from the medulla oblongata in the lower brainstem to the lumbar region of the vertebral column (backbone) of vertebrate animals. The center of the spinal c ...

, a series of short

evagination Endodermic evagination relates to the inner germ layers of cells of the very early embryo, from which is formed the lining of the digestive tract, of other internal organs, and of certain glands, implies the extension of a layer of body tissue to f ...

s from each segment grows

dorsally Standard anatomical terms of location are used to describe unambiguously the anatomy of humans and other animals. The terms, typically derived from Latin or Greek roots, describe something in its standard anatomical position. This position provi ...

and extends

caudally Standard anatomical terms of location are used to describe unambiguously the anatomy of humans and other animals. The terms, typically derived from Latin or Greek roots, describe something in its standard anatomical position. This position provi ...

, fusing successively from before backward to form the pronephric duct. This continues to grow caudalward until it opens into the ventral part of the

cloaca A cloaca ( ), : cloacae ( or ), or vent, is the rear orifice that serves as the only opening for the digestive (rectum), reproductive, and urinary tracts (if present) of many vertebrate animals. All amphibians, reptiles, birds, cartilagin ...

; beyond the

pronephros Pronephros is the most basic of the three excretory organs that develop in vertebrates, corresponding to the first stage of kidney development. It is succeeded by the mesonephros, which in fish and amphibians remains as the adult kidney. In am ...

it is termed the

. Thus, the mesonephric duct remains after the atrophy of the pronephros.

External links

Diagram at berkeley.edu

{{Authority control Embryology of urogenital system