Progestin And AdipoQ Receptor
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The progestin and adipoQ receptor (PAQR) family is a group of
receptor Receptor may refer to: * Sensory receptor, in physiology, any neurite structure that, on receiving environmental stimuli, produces an informative nerve impulse *Receptor (biochemistry), in biochemistry, a protein molecule that receives and respond ...
s related to but distinct from the
G protein-coupled receptor G protein-coupled receptors (GPCRs), also known as seven-(pass)-transmembrane domain receptors, 7TM receptors, heptahelical receptors, serpentine receptors, and G protein-linked receptors (GPLR), form a large group of evolutionarily related ...
family, which have the similar seven transmembrane structure, but the N-terminal is located on the inner side of the cell. It includes at least 11 receptors (PAQR1–PAQR11), including the adiponectin (adipoQ) receptors (AdipoRs), the
membrane progesterone receptor Membrane progesterone receptors (mPRs) are a group of cell surface receptors and membrane steroid receptors belonging to the progestin and adipoQ receptor (PAQR) family which bind the endogenous progestogen and neurosteroid progesterone, as well as ...
s (mPRs), and others. In 2016, the University of Tokyo announced that it would launch an investigation into claims of fabrication of AdipoRs identification data, as accused by an anonymous person/group called Ordinary_researchers.University of Tokyo to investigate data manipulation charges against six prominent research groups
ScienceInsider, Dennis Normile, Sep 20, 2016


List of PAQRs


AdipoRs

* PAQR1 (AdipoR1) * PAQR2 (AdipoR2)


mPRs

* PAQR5 (mPRγ) * PAQR6 (mPRδ) * PAQR7 (mPRα) *
PAQR8 Membrane progesterone receptor beta (mPRβ), or progestin and adipoQ receptor 8 (PAQR8), is a protein that in humans is encoded by the ''PAQR8'' gene. See also * Membrane progesterone receptor Membrane progesterone receptors (mPRs) are a group ...
(mPRβ) * PAQR9 (mPRϵ)


Others

* PAQR3 * PAQR4 * PAQR10 * PAQR11


References

Receptors {{receptor-stub