Procyanidin B2 is a

B type proanthocyanidin B type proanthocyanidins are a specific type of proanthocyanidin, which are a class of flavanoids. They are oligomers of flavan-3-ols. Dimeric B type proanthocyanidins These molecules have the molecular formula C30H26O12 (molar mass : 578.52 g/m ...

. Its structure is (−)-

Epicatechin Catechin is a flavan-3-ol, a type of secondary metabolite providing antioxidant roles in plants. It belongs to the subgroup of polyphenols called flavonoids. The name of the catechin chemical family derives from '' catechu'', which is the tann ...

-(4β→8)-(−)-epicatechin. Procyanidin B2 can be found in ''

Cinchona pubescens ''Cinchona pubescens'', also known as red cinchona and quina or kina (; ), is native to Central and South America. It is known as a medicinal plant for its bark's high quinine content- and has similar uses to '' C. officinalis'' in the production ...

'' (Chinchona: in the rind, bark, and cortex), in ''

Cinnamomum verum ''Cinnamomum verum'' ( synonym ''Cinnamomum zeylanicum'', also called true cinnamon tree or Ceylon cinnamon tree) is a small evergreen tree belonging to the family Lauraceae, native to Sri Lanka. The inner bark of the tree is historically regard ...

'' (Ceylon cinnamon: in the rind, bark, and cortex), in ''

Crataegus monogyna ''Crataegus monogyna'', known as common hawthorn, whitethorn, one-seed hawthorn, or single-seeded hawthorn, is a species of flowering plant in the rose family, Rosaceae. It grows to about tall, producing plant sexuality, hermaphrodite flowers i ...

'' (Common hawthorn: in the flower and blossom), in ''

Uncaria guianensis ''Uncaria guianensis'', the cat's claw, is a plant species in the genus ''Uncaria'' found in the Amazon biome. Other names for the plant include ''uña de gato'', ''Paraguayo'' and ''vincaria''. ''Uncaria guianensis'' contains many phytochemica ...

'' (Cat's claw: in the root), in ''

Vitis vinifera ''Vitis vinifera'', the common grape vine, is a species of flowering plant, native to the Mediterranean Basin, Mediterranean region, Central Europe, and southwestern Asia, from Morocco and Portugal north to southern Germany and east to northern ...

'' (Common grape vine: in the leaf), in ''

Litchi chinensis Lychee ( , ; ''Litchi chinensis''; ) is a monotypic taxon and the sole member in the genus ''Litchi'' in the Sapindus, soapberry family, Sapindaceae. There are three distinct subspecies of lychee. The most common is the Indochinese lychee fo ...

'' (litchi: in the pericarp),Immunomodulatory and anticancer activities of flavonoids extracted from litchi (Litchi chinensis Sonn.) pericarp. Mouming Zhao; Bao Yang; Jinshui Wang; Yang Liu; Limei Yu; Yueming Jiang, 2007
/ref> in the

apple An apple is a round, edible fruit produced by an apple tree (''Malus'' spp.). Fruit trees of the orchard or domestic apple (''Malus domestica''), the most widely grown in the genus, are agriculture, cultivated worldwide. The tree originated ...

, and in ''

Ecdysanthera utilis ''Urceola micrantha'' is a plant species in the family Apocynaceae. It is a shrub widespread across much of East Asia, Southeast Asia, and the Himalayas. In Taïwan, it is used in folk medicine as an analgesic, antiphlogistic and spasmolytic a ...

''. Procyanidin B2 can be converted into procyanidin A2 by radical oxidation using

1,1-diphenyl-2-picrylhydrazyl DPPH is a common abbreviation for the organic chemical compound 2,2-diphenyl-1-picrylhydrazyl. It is a dark-colored crystalline powder composed of stable free radical molecules. DPPH has two major applications, both in laboratory research: one is ...

(DPPH) radicals under neutral conditions. Procyanidin B2 has been shown to inhibit the formation of the

advanced glycation end-product Advanced glycation end-products (AGEs) are proteins or lipids that become Glycation, glycated as a result of exposure to sugars. They are a bio-marker implicated in aging and the development, or worsening, of many degenerative diseases, such as dia ...

s pentosidine, carboxymethyllysine (CML), and

methylglyoxal Methylglyoxal (MGO) is the organic compound with the formula CH3C(O)CHO. It is a reduced derivative of pyruvic acid. It is a reactive compound that is implicated in the biology of diabetes. Methylglyoxal is produced industrially by degradation ...

(MGO).

References

Procyanidin dimers {{Aromatic-stub

See also

References