Prefrontal Area 11
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Brodmann area 11 is one of Brodmann's cytologically defined regions of the brain. It is in the
orbitofrontal cortex The orbitofrontal cortex (OFC) is a prefrontal cortex region in the frontal lobes of the brain which is involved in the cognitive process of decision-making. In non-human primates it consists of the association cortex areas Brodmann area 11, 1 ...
which is above the eye sockets (orbitae). It is involved in
decision making In psychology, decision-making (also spelled decision making and decisionmaking) is regarded as the cognitive process resulting in the selection of a belief or a course of action among several possible alternative options. It could be either ra ...
, processing rewards, and encoding new information into long-term memory.


In humans

Brodmann area 11, or BA11, is part of the frontal
cortex Cortex or cortical may refer to: Biology * Cortex (anatomy), the outermost layer of an organ ** Cerebral cortex, the outer layer of the vertebrate cerebrum, part of which is the ''forebrain'' *** Motor cortex, the regions of the cerebral cortex i ...
in the
human brain The human brain is the central organ (anatomy), organ of the nervous system, and with the spinal cord, comprises the central nervous system. It consists of the cerebrum, the brainstem and the cerebellum. The brain controls most of the activi ...
. BA11 is the part of the
orbitofrontal cortex The orbitofrontal cortex (OFC) is a prefrontal cortex region in the frontal lobes of the brain which is involved in the cognitive process of decision-making. In non-human primates it consists of the association cortex areas Brodmann area 11, 1 ...
that covers the medial portion of the ventral surface of the frontal lobe. Prefrontal area 11 of Brodmann-1909 is a subdivision of the frontal lobe in the human defined on the basis of
cytoarchitecture Cytoarchitecture (from Greek κύτος 'cell' and ἀρχιτεκτονική 'architecture'), also known as cytoarchitectonics, is the study of the cellular composition of the central nervous system's tissues under the microscope. Cytoarchit ...
. Defined and illustrated in Brodmann-1909, it included the areas subsequently illustrated in Brodmann-10 as prefrontal area 11 and rostral area 12. Area 11 is a subdivision of the cytoarchitecturally defined frontal region of cerebral cortex of the human. As illustrated in Brodmann-10, It constitutes most of the orbital gyri,
gyrus rectus The portion of the inferior frontal lobe immediately adjacent to the longitudinal fissure (and medial to the medial orbital gyrus and olfactory tract) is named the straight gyrus,(or gyrus rectus) and is continuous with the superior frontal gyru ...
and the most rostral portion of the
superior frontal gyrus In neuroanatomy, the superior frontal gyrus (SFG, also marginal gyrus) is a gyrus – a ridge on the brain's cerebral cortex – which makes up about one third of the frontal lobe. It is bounded laterally by the superior frontal sulcus. The su ...
. It is bounded medially by the inferior rostral sulcus (H) and laterally approximately by the frontomarginal sulcus (H). Cytoarchitecturally it is bounded on the rostral and lateral aspects of the hemisphere by the
frontopolar area 10 Brodmann area 10 (BA10, frontopolar prefrontal cortex, rostrolateral prefrontal cortex, or anterior prefrontal cortex) is the anterior-most portion of the prefrontal cortex in the human brain. BA10 was originally defined broadly in terms of its c ...
, the
orbital area 47 Brodmann area 47, or BA47, is part of the frontal cortex in the human brain. It curves from the lateral surface of the frontal lobe into the ventral (orbital) frontal cortex. It is inferior to BA10 and BA45, and lateral to BA11. This cytoarc ...
, and the triangular area 45; on the medial surface it is bounded dorsally by the
rostral area 12 Brodmann area 12 is a subdivision of the cerebral cortex of the guenon defined on the basis of cytoarchitecture. It occupies the most rostral portion of the frontal lobe. Brodmann-1909 did not regard it as homologous, either topographically or cy ...
and caudally by the
subgenual area 25 Brodmann area 25 (BA25) is the subgenual area, area subgenualis or subgenual cingulate area in the cerebral cortex of the brain and delineated based on its cytoarchitectonic characteristics. It is the 25th "Brodmann area" defined by Korbinian Br ...
. In an earlier map, the area labeled 11, i.e., prefrontal
area 11 of Brodmann Brodmann area 11 is one of Brodmann's cytologically defined regions of the brain. It is in the orbitofrontal cortex which is above the eye sockets (orbitae). It is involved in decision making, processing rewards, and encoding new information ...
-1909, was larger; it included the area now designated rostral area 12.


In guenon monkeys

Brodmann area 11 is a subdivision of the frontal lobe of the
guenon The guenons (, ) are Old World monkeys of the genus ''Cercopithecus'' (). Not all members of this genus have the word "guenon" in their common names; also, because of changes in scientific classification, some monkeys in other genera may have co ...
monkey defined on the basis of cytoarchitecture (Brodmann-1905). Distinctive features: area 11 lacks an internal granular layer (IV); larger
pyramidal cell Pyramidal cells, or pyramidal neurons, are a type of multipolar neuron found in areas of the brain including the cerebral cortex, the hippocampus, and the amygdala. Pyramidal cells are the primary excitation units of the mammalian prefrontal cort ...
s of sublayer 3b of the external
pyramidal layer The cerebral cortex, also known as the cerebral mantle, is the outer layer of neural tissue of the cerebrum of the brain in humans and other mammals. It is the largest site of neural integration in the central nervous system, and plays a key ...
(III) merge with a denser self-contained collection of cells in the internal pyramidal layer (V); similar to
area 10 of Brodmann Brodmann area 10 (BA10, frontopolar prefrontal cortex, rostrolateral prefrontal cortex, or anterior prefrontal cortex) is the anterior-most portion of the prefrontal cortex in the human brain. BA10 was originally defined broadly in terms of its c ...
-1909 is the presence in the
multiform layer The cerebral cortex, also known as the cerebral mantle, is the outer layer of neural tissue of the cerebrum of the brain in humans and other mammal A mammal () is a vertebrate animal of the Class (biology), class Mammalia (). Mammal ...
(VI) of trains of cells oriented parallel to the cortical surface separated by acellular fiber bundles; a thick molecular layer (I); a relatively narrow overall cortical thickness; and a gradual transition from the multiform layer (VI) to the subcortical
white matter White matter refers to areas of the central nervous system that are mainly made up of myelinated axons, also called Nerve tract, tracts. Long thought to be passive tissue, white matter affects learning and brain functions, modulating the distr ...
.


Images

File:Brodmann area 11 animation small.gif, Animation. File:Brodmann area 11 frontal.jpg, front view. File:Brodmann area 11 lateral.jpg, Lateral view.


See also

*
Brodmann area A Brodmann area is a region of the cerebral cortex, in the human or other primate brain, defined by its cytoarchitecture, or histological structure and organization of cells. The concept was first introduced by the German anatomist Korbinian B ...
*
List of regions in the human brain The human brain anatomical regions are ordered following standard neuroanatomy hierarchies. Functional, connective, and developmental regions are listed in parentheses where appropriate. Hindbrain (rhombencephalon) Myelencephalon * M ...


References


External links

* For Neuroanatomy of this area in guenon se
BrainInfo
* For Neuroanatomy of this area in human se
BrainInfo
{{Prosencephalon 11 Frontal lobe