Polyvinylpolypyrrolidone (polyvinyl polypyrrolidone, PVPP, crospovidone, crospolividone, or E1202) is a highly
cross-linked modification of
polyvinylpyrrolidone (PVP).
The
cross-linked form of PVP is used as a disintegrant (see also
excipients) in pharmaceutical tablets. PVPP is a highly cross-linked version of PVP, making it insoluble in water, though it still absorbs water and swells very rapidly generating a swelling force. This property makes it useful as a disintegrant in
tablets.
PVPP can be used as a drug, taken as a tablet or
suspension to absorb compounds (so-called
endotoxins) that cause
diarrhea. (''Cf.''
bone char,
charcoal.)
It is also used as a
fining to extract impurities (via agglomeration followed by filtration). It is used in
winemaking
Winemaking, wine-making, or vinification is the production of wine, starting with the selection of the fruit, its Ethanol fermentation, fermentation into alcohol, and the bottling of the finished liquid. The history of wine-making stretches over ...
. Using the same principle it is used to remove polyphenols in
beer
Beer is an alcoholic beverage produced by the brewing and fermentation of starches from cereal grain—most commonly malted barley, although wheat, maize (corn), rice, and oats are also used. The grain is mashed to convert starch in the ...
production and thus clear beers with stable foam are produced. One such commercial product is called Polyclar. PVPP forms bonds similar to
peptidic bonds in protein (especially, like
proline residues) and that is why it can precipitate
tannin
Tannins (or tannoids) are a class of astringent, polyphenolic biomolecules that bind to and Precipitation (chemistry), precipitate proteins and various other organic compounds including amino acids and alkaloids. The term ''tannin'' is widel ...
s the same way as proteins do.
PVPP has
E number
E numbers, short for Europe numbers, are codes for substances used as food additives, including those found naturally in many foods, such as vitamin C, for use within the European Union (EU) and European Free Trade Association (EFTA). Commonly ...
code E1202 and is used as a
stabiliser.
See also
*
Polyethylene glycol-polyvinyl alcohol
References
{{reflist, 30em
Vinyl polymers
Food additives
Pyrrolidones
Excipients
E-number additives