Polyallylamine hydrochloride (CAS No. 71550-12-4) is a cationic
polyelectrolyte
Polyelectrolytes are polymers whose repeating units bear an electrolyte group. Polycations and polyanions are polyelectrolytes. These groups dissociate in aqueous solutions (water), making the polymers charged. Polyelectrolyte properties are t ...
prepared by the polymerization of
allylamine
Allylamine is an organic compound with the formula C3H5NH2. This colorless liquid is the simplest stable Alkene, unsaturated amine.
Production and reactions
All three allylamines, mono-, di-, and triallylamine, are produced by the treating allyl ...
. It can be used in combination with an anionic polyelectrolyte like
poly(sodium styrene sulfonate) to form a layer-by-layer adsorbed film of negatively and positively charged polymers.
Poly(allylamine hydrochloride) has many biomedical applications. The most prominent use of this polyelectrolyte is in the field of cell encapsulation. A layer by layer method is used by alternating positively and negatively charged polyelectrolytes to build a barrier between the cell and the harsher outside environment. Upon cell lysis, the capsule of layered polyelectrolytes maintains its structural integrity and can be used for purposes such as drug delivery.
[{{cite journal, last=Antipov, first=A, author2=Gleb B. Sukhorukov , author3=Edwin Donath , author4=Helmuth Moehwald , title=Sustained Release Properties of Polyelectrolyte Multilayer Capsules, journal=J. Phys. Chem. B, year=2001, volume=105, issue=12, pages=2281–2284, doi=10.1021/jp002184+]
References
Organic polymers
Plastics
Polyelectrolytes