Pliva d.o.o. is a

pharmaceutical Medication (also called medicament, medicine, pharmaceutical drug, medicinal product, medicinal drug or simply drug) is a drug used to diagnose, cure, treat, or prevent disease. Drug therapy ( pharmacotherapy) is an important part of the ...

company based in

Zagreb Zagreb ( ) is the capital (political), capital and List of cities and towns in Croatia#List of cities and towns, largest city of Croatia. It is in the Northern Croatia, north of the country, along the Sava river, at the southern slopes of the ...

Croatia Croatia, officially the Republic of Croatia, is a country in Central Europe, Central and Southeast Europe, on the coast of the Adriatic Sea. It borders Slovenia to the northwest, Hungary to the northeast, Serbia to the east, Bosnia and Herze ...

that primarily manufactures and sells

generic drug A generic drug is a pharmaceutical drug that contains the same chemical substance as a drug that was originally protected by chemical patents. Generic drugs are allowed for sale after the patents on the original drugs expire. Because the active ch ...

s. It is a subsidiary of

Teva Pharmaceuticals Teva Pharmaceutical Industries Ltd. (also known as Teva Pharmaceuticals) is an Israeli multinational Pharmaceutical industry, pharmaceutical company. Teva specializes primarily in generic drugs, but other business interests include branded-drug ...

. Pliva is one of the world's largest producers of

generic Generic or generics may refer to: In business * Generic term, a common name used for a range or class of similar things not protected by trademark * Generic brand, a brand for a product that does not have an associated brand or trademark, other ...

Adderall Adderall and Mydayis are trade names for a combination drug containing four salts of amphetamine. The mixture is composed of equal parts racemic amphetamine and dextroamphetamine, which produces a (3:1) ratio between dextroamphetamine and l ...

History

The company was founded in 1921. A team of Pliva's researchers,

Gabrijela Kobrehel Gabrijela () is a Croatian given name. It may refer to: *Gabrijela Bartulović Gabrijela Bartulović (née Bešen; born 6 December 1994) is a Croatian handball player for Dunaújvárosi Kohász KA and the Croatia women's national handball team, ...

, Gorjana Radobolja-Lazarevski and

Zrinka Tamburašev Zrinka Tamburašev was a Croatian scientist known for her work in the development of antibiotics such as oxytetracycline and azithromycin. Early life Tamburašev was born in Sisak, Kingdom of Yugoslavia, in 1921. She graduated in 1948 from the ...

led by Dr.

Slobodan Đokić Slobodan ( sr-Cyrl, Слободан) is a Serbo-Croatian masculine given name which means "free" (''sloboda'' / meaning "freedom, liberty") used among other South Slavs as well. It was coined by Serbian liberal politician Vladimir Jovanović w ...

, discovered

azithromycin Azithromycin, sold under the brand names Zithromax (in oral form) and Azasite (as an eye drop), is an antibiotic medication used for the treatment of several bacterial infections. This includes otitis media, middle ear infections, strep throa ...

in 1980. In June 2002, the company acquired Sidmak for $152.9 million. Also in June 2002, Zeljko Peric, the

chief financial officer A chief financial officer (CFO) is an officer of a company or organization who is assigned the primary responsibility for making decisions for the company for projects and its finances; i.a.: financial planning, management of financial risks, ...

of the company, resigned. In May 2004, the company received approval from the

Food and Drug Administration The United States Food and Drug Administration (FDA or US FDA) is a List of United States federal agencies, federal agency of the United States Department of Health and Human Services, Department of Health and Human Services. The FDA is respo ...

to sell

trospium chloride Trospium chloride is a muscarinic antagonist used to treat overactive bladder. It has side effects typical of this class of drugs, namely dry mouth, stomach upset, and constipation; these side effects cause problems with people taking their med ...

. In June 2005, the company received approval to sell a generic version of

erythropoietin Erythropoietin (; EPO), also known as erythropoetin, haematopoietin, or haemopoietin, is a glycoprotein cytokine secreted mainly by the kidneys in response to cellular hypoxia; it stimulates red blood cell production ( erythropoiesis) in th ...

in Croatia. In November 2005, the company received approval from the

to sell a generic version of

Azithromycin Azithromycin, sold under the brand names Zithromax (in oral form) and Azasite (as an eye drop), is an antibiotic medication used for the treatment of several bacterial infections. This includes otitis media, middle ear infections, strep throa ...

Citalopram Citalopram, sold under the brand name Celexa among others, is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. It is used to treat major depressive disorder, obsessive compulsive disorder, panic disorder, and soci ...

, and

Ondansetron Ondansetron, sold under the brand name Zofran among others, is a medication used to prevent nausea and vomiting caused by chemotherapy, radiation therapy, migraines, or surgery. It is also effective for treating gastroenteritis. It can be giv ...

. In October 2006,

Barr Pharmaceuticals Barr Pharmaceuticals was an American specialty and generic drug manufacturer with operations in 30 countries. Approximately 75% of the company's revenues came from the sale of generic drugs, including 18% of sales which were from the sale of oral ...

acquired Pliva. On December 23, 2008, Barr Pharmaceuticals was acquired by

and the company became part of Teva Active Pharmaceutical Ingredients (TAPI).

References

{{Authority control 1921 establishments in Croatia Manufacturing companies based in Zagreb Croatian brands Pharmaceutical companies established in 1921 Pharmaceutical companies of Croatia 2006 mergers and acquisitions