Philip Handler
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Philip Handler (August 13, 1917 – December 29, 1981) was an American
nutritionist A nutritionist is a person who advises others on matters of food and Human nutrition, nutrition and their impacts on health. Some people specialize in particular areas, such as sports nutrition, public health, or animal nutrition, among other disci ...
, and biochemist. He was President of the
United States National Academy of Sciences The National Academy of Sciences (NAS) is a United States nonprofit, non-governmental organization. NAS is part of the National Academies of Sciences, Engineering, and Medicine, along with the National Academy of Engineering (NAE) and the Nati ...
for two terms from 1969 to 1981. He was also a recipient of the
National Medal of Science The National Medal of Science is an honor bestowed by the President of the United States to individuals in science and engineering who have made important contributions to the advancement of knowledge in the fields of behavioral science, behavior ...
.


Biography

Handler grew up in a Jewish family in New York City. He received his B.S. degree from the
City College of New York The City College of the City University of New York (also known as the City College of New York, or simply City College or CCNY) is a Public university, public research university within the City University of New York (CUNY) system in New York ...
in 1936 and his Ph.D. from
University of Illinois The University of Illinois Urbana-Champaign (UIUC, U of I, Illinois, or University of Illinois) is a public university, public land-grant university, land-grant research university in the Champaign–Urbana metropolitan area, Illinois, United ...
in 1939. He taught at
Duke University Duke University is a Private university, private research university in Durham, North Carolina, United States. Founded by Methodists and Quakers in the present-day city of Trinity, North Carolina, Trinity in 1838, the school moved to Durham in 1 ...
where he was named the youngest chairman of the Department of Biochemistry, at 35. Handler remained at Duke until 1969, when he accepted the position of president of the
National Academy of Sciences The National Academy of Sciences (NAS) is a United States nonprofit, NGO, non-governmental organization. NAS is part of the National Academies of Sciences, Engineering, and Medicine, along with the National Academy of Engineering (NAE) and the ...
. As a biochemist, he published more than 200 papers on nutrition and metabolic activity. He was elected to the
National Academy of Sciences The National Academy of Sciences (NAS) is a United States nonprofit, NGO, non-governmental organization. NAS is part of the National Academies of Sciences, Engineering, and Medicine, along with the National Academy of Engineering (NAE) and the ...
in 1964. He received the
National Medal of Science The National Medal of Science is an honor bestowed by the President of the United States to individuals in science and engineering who have made important contributions to the advancement of knowledge in the fields of behavioral science, behavior ...
in 1981 for "his outstanding contribution to biochemical research, resulting in significant contributions to mankind, including research which led to a clearer understanding of
pellagra Pellagra is a disease caused by a lack of the vitamin niacin (vitamin B3). Symptoms include inflamed skin, diarrhea, dementia, and sores in the mouth. Areas of the skin exposed to friction and radiation are typically affected first. Over tim ...
". His research led to the first understanding of nicotinic acid deficiency and the discovery of the tryptophan-nicotinic acid relationship. Handler also provided an understanding of the oxidation of
sarcosine Sarcosine, also known as ''N''-methylglycine, or monomethylglycine, is a amino acid with the formula CH3N(H)CH2CO2H. It exists at neutral pH as the zwitterion CH3N+(H)2CH2CO2−, which can be obtained as a white, water-soluble powder. Like some ...
to
glycine Glycine (symbol Gly or G; ) is an amino acid that has a single hydrogen atom as its side chain. It is the simplest stable amino acid. Glycine is one of the proteinogenic amino acids. It is encoded by all the codons starting with GG (G ...
and
formaldehyde Formaldehyde ( , ) (systematic name methanal) is an organic compound with the chemical formula and structure , more precisely . The compound is a pungent, colourless gas that polymerises spontaneously into paraformaldehyde. It is stored as ...
, which led to the importance of single-carbon atoms in metabolism. His final work showed that
methionine Methionine (symbol Met or M) () is an essential amino acid in humans. As the precursor of other non-essential amino acids such as cysteine and taurine, versatile compounds such as SAM-e, and the important antioxidant glutathione, methionine play ...
is the only
methyl In organic chemistry, a methyl group is an alkyl derived from methane, containing one carbon atom bonded to three hydrogen atoms, having chemical formula (whereas normal methane has the formula ). In formulas, the group is often abbreviated as ...
donor in mammalian metabolism and that there is no pool of methyl groups. As President of the National Academy of Sciences, Handler was instrumental in opening a dialog on American-Soviet cooperation in outer space with his counterpart at the
Soviet Academy of Sciences The Academy of Sciences of the Soviet Union was the highest scientific institution of the Soviet Union from 1925 to 1991. It united the country's leading scientists and was subordinated directly to the Council of Ministers of the Soviet Union (un ...
in 1970. The discussions would ultimately lead to a joint spaceflight in 1975, the Apollo-Soyuz Test Project. Handler was also responsible for perhaps one of the most notable statues relating to science in the United States: that of
Albert Einstein Albert Einstein (14 March 187918 April 1955) was a German-born theoretical physicist who is best known for developing the theory of relativity. Einstein also made important contributions to quantum mechanics. His mass–energy equivalence f ...
at the grounds of the National Academy of Sciences in Washington, DC. Handler was also involved in the creation of the US Department of Health, Education and Welfare (HEW), the predecessor to the
US Department of Health and Human Services The United States Department of Health and Human Services (HHS) is a cabinet-level executive branch department of the US federal government created to protect the health of the US people and providing essential human services. Its motto is ...
. Within HEW, Handler had a significant impact on the creation of a multitude of centers within the
National Institutes of Health The National Institutes of Health (NIH) is the primary agency of the United States government responsible for biomedical and public health research. It was founded in 1887 and is part of the United States Department of Health and Human Service ...
. He spurred in part by a growing interest in the biosciences, his position on various governmental committees, and the book ''Biology & The Future of Man'', which read like a blueprint for a generation of work in the life sciences. Rather abruptly, Handler died in Boston on December 29, 1981, from pneumonia, just short of six months after leaving office at the Academy. Instead of returning to Duke University as planned, he remained in the hospital following his admission for a thorough checkup in August 1981. He chose to have his ashes placed alongside his colleagues' at Duke University Medical Center, where he began his academic research career.


Positions held


Employment

* 1937–1939 Junior Chemist, U. S. Regional Soybean Byproducts Laboratory * Duke University School of Medicine: ** 1939–1942 Fellow and Instructor, Nutrition and Physiology ** 1942–1945 Assistant Professor of Physiology ** 1945–1950 Associate Professor of Biochemistry ** 1950–1961 Professor of Biochemistry and Chairman of the Department ** 1961–1969 James B. Duke Professor of Biochemistry (on leave 1969–1981) and Chairman of the Department ** 1969–1981 President, National Academy of Sciences ** 1970–1981 Distinguished Professor of Medical Sciences, George Washington University


Public Service

Governmental Positions * 1952–1962 Consultant, Veteran's Administration * 1964–1968
President's Science Advisory Committee The President's Science Advisory Committee (PSAC) was created on November 21, 1957, by President of the United States Dwight D. Eisenhower, as a direct response to the Soviet launching of the Sputnik 1 and Sputnik 2 satellites. PSAC was an upgra ...
* 1968–1974 President's Science Advisory Committee * 1969–1981 Committee on National Medal of Science * 1980 Chairman, U. S. Delegation to the Scientific Forum of the Conference on Security and Cooperation in Europe, Hamburg * National Institutes of Health: ** 1953–1956 Biochemistry Study Section ** 1956–1958 Chairman, Biochemistry Study Section ** 1956–1959 Committee on Health Sciences Training ** 1958–1961 National Advisory Health Council ** 1963–1967 National Advisory Council on Research Resources and Facilities * National Science Foundation: ** 1958–1960 Panel on Biological Research Facilities ** 1960–1962 Divisional Committee for Biology and Medicine ** 1962–1974
National Science Board The National Science Board (NSB) of the United States establishes the policies of the National Science Foundation (NSF) within the framework of applicable national policies set forth by the President of the United States, president and the United ...
, Member ** 1964–1966 National Science Board, Vice-Chairman ** 1966–1970 National Science Board, Chairman Non-Government * 1953–1965 Federation of American Societies for Experimental Biology, Member of Board (1953–1965); Executive Committee (1959–1965); Chairman (1964–1965) * 1953–1968 American Society of Biological Chemists, Secretary (1953–1958); Councillor (1958–1961); President-elect (1961); President (1962); Chairman, Publications Committee (1965–1968) * 1967–1981 National Academy of Sciences, Chairman, Committee on the Life Sciences (1967–1970); Councillor (1966–1969); President (1969–1981) * 1969–1981 Board of Trustees,
Rockefeller University The Rockefeller University is a Private university, private Medical research, biomedical Research university, research and graduate-only university in New York City, New York. It focuses primarily on the biological and medical sciences and pro ...
* 1973–1979 Board of Trustees, Nutrition Foundation * 1974–1981 Board of Governors,
Hebrew University of Jerusalem The Hebrew University of Jerusalem (HUJI; ) is an Israeli public university, public research university based in Jerusalem. Co-founded by Albert Einstein and Chaim Weizmann in July 1918, the public university officially opened on 1 April 1925. ...
* 1981 Board of Governors,
Weizmann Institute of Science The Weizmann Institute of Science ( ''Machon Weizmann LeMada'') is a Public university, public research university in Rehovot, Israel, established in 1934, fourteen years before the State of Israel was founded. Unlike other List of Israeli uni ...


Honors

* Twenty-Eight Honorary Doctorates including: City University of New York (1970),
University of North Carolina at Chapel Hill The University of North Carolina at Chapel Hill (UNC, UNC–Chapel Hill, or simply Carolina) is a public university, public research university in Chapel Hill, North Carolina, United States. Chartered in 1789, the university first began enrolli ...
(1971),
University of Connecticut The University of Connecticut (UConn) is a public land-grant research university system with its main campus in Storrs, Connecticut, United States. It was founded in 1881 as the Storrs Agricultural School, named after two benefactors. In 1893, ...
(1971),
Temple University Temple University (Temple or TU) is a public university, public Commonwealth System of Higher Education, state-related research university in Philadelphia, Philadelphia, Pennsylvania, United States. It was founded in 1884 by the Baptist ministe ...
(1972),
George Washington University The George Washington University (GW or GWU) is a Private university, private University charter#Federal, federally-chartered research university in Washington, D.C., United States. Originally named Columbian College, it was chartered in 1821 by ...
(1973),
Michigan State University Michigan State University (Michigan State or MSU) is a public university, public Land-grant university, land-grant research university in East Lansing, Michigan, United States. It was founded in 1855 as the Agricultural College of the State o ...
(1975), University of Alaska (1977),
Ohio State University The Ohio State University (Ohio State or OSU) is a public university, public Land-grant university, land-grant research university in Columbus, Ohio, United States. A member of the University System of Ohio, it was founded in 1870. It is one ...
(1978), University of Illinois (1979),
University of Maryland The University of Maryland, College Park (University of Maryland, UMD, or simply Maryland) is a public land-grant research university in College Park, Maryland, United States. Founded in 1856, UMD is the flagship institution of the Univ ...
(1979),
University of Florida The University of Florida (Florida or UF) is a public university, public land-grant university, land-grant research university in Gainesville, Florida, United States. It is a senior member of the State University System of Florida and a preem ...
(1979),
Medical University of South Carolina The Medical University of South Carolina (MUSC) is a public medical school in Charleston, South Carolina. It opened in 1824 as a small private college aimed at training physicians and has since established hospitals and medical facilities acros ...
(1980),
Washington University in St. Louis Washington University in St. Louis (WashU) is a private research university in St. Louis, Missouri, United States. Founded in 1853 by a group of civic leaders and named for George Washington, the university spans 355 acres across its Danforth ...
(1980). * 1943 C.B. Mayer Award, New York Academy of Medicine * 1964 Member, National Academy of Sciences * 1964 Townsend Harris Medal, City College of New York * 1966 Annual Orator, Harvey Gushing Society * 1966 Fellow,
American Academy of Arts and Sciences The American Academy of Arts and Sciences (The Academy) is one of the oldest learned societies in the United States. It was founded in 1780 during the American Revolution by John Adams, John Hancock, James Bowdoin, Andrew Oliver, and other ...
* 1966 Sigma Xi National Lecturer * 1969 Annual Award for Distinguished Contributions to Medical Sciences,
American Medical Association The American Medical Association (AMA) is an American professional association and lobbying group of physicians and medical students. This medical association was founded in 1847 and is headquartered in Chicago, Illinois. Membership was 271,660 ...
* 1969 Member,
American Philosophical Society The American Philosophical Society (APS) is an American scholarly organization and learned society founded in 1743 in Philadelphia that promotes knowledge in the humanities and natural sciences through research, professional meetings, publicat ...
* 1970 Benjamin Franklin Fellow, Royal Society for the Encouragement of Arts, Manufacture and Commerce * 1970 Honorary Member,
Swiss Academy of Natural Sciences The Swiss Academy of Sciences (SCNAT) is a Switzerland, Swiss national association founded in 1815.Mission
* 1972 Alumni Achievement Award,
University of Illinois The University of Illinois Urbana-Champaign (UIUC, U of I, Illinois, or University of Illinois) is a public university, public land-grant university, land-grant research university in the Champaign–Urbana metropolitan area, Illinois, United ...
* 1972 German Academy of Natural Sciences, Leopoldina * 1973 Honorary Member,
American Institute of Chemists The American Institute of Chemists (AIC) is an organization founded in 1923 with the goal of advancing the chemistry profession in the United States. The institute is known for its yearly awards recognizing contributions of individuals in this fie ...
* 1974 Honorary Member, National Academy of Medicine of Mexico * 1975 Copernicus Medal,
Polish Academy of Sciences The Polish Academy of Sciences (, PAN) is a Polish state-sponsored institution of higher learning. Headquartered in Warsaw, it is responsible for spearheading the development of science across the country by a society of distinguished scholars a ...
* 1977 The Great Cross of Honor with Star, Government of Austria * 1977 Insignia of Commander of the Order of Leopold II, King of Belgium * 1978 Honorary Member, Imperial Iranian Academy of Sciences * 1978 Commander, Order of Merit, People's Republic of Poland * 1979 Distinguished Public Service Award, National Science Foundation * 1981 National Medal of Science


Selected quotes

Many of the quotes were found in the Memorial Program honoring his life and held at the National Academy of Sciences.Memorial Service Program handed out at the National Academy of Sciences. Washington, D.C. February 8, 1982 "I am committed to defense of the human rights of all persons, but those of scientists in particular. Not so much because humanity may be denied the fruits of their science, but because they are precious as human beings; because abrogation of their rights is injurious to all mankind; because, as thoughtful intellectuals, scientists not infrequently become involved in the defense of the human rights of others..." – "Science in a Free Society" The
Phi Beta Kappa The Phi Beta Kappa Society () is the oldest academic honor society in the United States. It was founded in 1776 at the College of William & Mary in Virginia. Phi Beta Kappa aims to promote and advocate excellence in the liberal arts and sciences, ...
Bicentennial Lecture. College of William and Mary. December 6, 1976 "Creative scientific research is one of the very purposes of our society akin to imaginative scholarship in the humanities and innovation in the arts. Surely, no other course available to this civilization is as hopeful as the continuing subtle interplay of science and developing technology." From "The University in a World in Transition." The Convocation Address at the One Hundred and Fiftieth Anniversary of the University of Virginia. October 21, 1969. "Do not fear change – help to guide it. Every technology since fire and the wheel confronted humanity simultaneously with the prospect of great benefit – and of considerable hazard, with potential for good and for evil." From "Science in a Free Society" A Commencement Ceremony Address. Southwestern at Memphis. May 30, 1977.


References

*


External links


"Philip Handler 1917–1981: A Biographical Memoir"
by Emil L. Smith and Robert L. Hill. National Academy of Sciences, 1985.

{{DEFAULTSORT:Handler, Philip 1917 births 1981 deaths Members of the United States National Academy of Sciences Presidents of the United States National Academy of Sciences 20th-century American biochemists Jewish American scientists National Medal of Science laureates American nutritionists 20th-century American Jews City College of New York alumni University of Illinois Urbana-Champaign alumni Duke University School of Medicine faculty