Phillips Wesley Robbins is a

professor emeritus ''Emeritus/Emerita'' () is an honorary title granted to someone who retirement, retires from a position of distinction, most commonly an academic faculty position, but is allowed to continue using the previous title, as in "professor emeritus". ...

in the department of molecular and cell biology at the

Boston University Boston University (BU) is a Private university, private research university in Boston, Massachusetts, United States. BU was founded in 1839 by a group of Boston Methodism, Methodists with its original campus in Newbury (town), Vermont, Newbur ...

School of Dental Medicine. He moved to BU in 1998 following a career of almost 40 years on the faculty at the

Massachusetts Institute of Technology The Massachusetts Institute of Technology (MIT) is a Private university, private research university in Cambridge, Massachusetts, United States. Established in 1861, MIT has played a significant role in the development of many areas of moder ...

Early life and education

Robbins was born in 1930 in

Barre, Massachusetts Barre ( ) is a town in Worcester County, Massachusetts, United States. The population was 5,530 at the 2020 census. History Located on the ancestral homeland of the Nipmuc, the area was first settled by Europeans in 1720 and referred to as th ...

and attended high school in

West Springfield, Massachusetts West Springfield is a city in Hampden County, Massachusetts, United States. It is part of the Springfield, Massachusetts Metropolitan Statistical Area. The population was 28,835 at the 2020 United States Census. The city is also known as "West ...

. He later described a high school physics course as an inspiration for his plans for a science career, though he continued to consider following the family tradition by becoming a medical

missionary A missionary is a member of a Religious denomination, religious group who is sent into an area in order to promote its faith or provide services to people, such as education, literacy, social justice, health care, and economic development.Thoma ...

. He settled on

biochemistry Biochemistry, or biological chemistry, is the study of chemical processes within and relating to living organisms. A sub-discipline of both chemistry and biology, biochemistry may be divided into three fields: structural biology, enzymology, a ...

as his chosen field as an undergraduate at

DePauw University DePauw University ( ) is a private liberal arts college in Greencastle, Indiana, United States. It was founded in 1837 as Indiana Asbury College and changed its name to DePauw University in 1884. The college has a Methodist heritage and was ...

, from which he graduated in 1952. He received his Ph.D. in 1955 from the

University of Illinois The University of Illinois Urbana-Champaign (UIUC, U of I, Illinois, or University of Illinois) is a public university, public land-grant university, land-grant research university in the Champaign–Urbana metropolitan area, Illinois, United ...

under the supervision of Herbert E. Carter and then became a

postdoctoral fellow A postdoctoral fellow, postdoctoral researcher, or simply postdoc, is a person professionally conducting research after the completion of their doctoral studies (typically a PhD). Postdocs most commonly, but not always, have a temporary academ ...

with

Fritz Lipmann Fritz Albert Lipmann (; June 12, 1899 – July 24, 1986) was a German-American biochemist and a co-discoverer in 1945 of coenzyme A. For this, together with other research on coenzyme A, he was awarded the Nobel Prize in Physiology or Medicine in ...

, first at

Massachusetts General Hospital Massachusetts General Hospital (Mass General or MGH) is a teaching hospital located in the West End neighborhood of Boston, Massachusetts. It is the original and largest clinical education and research facility of Harvard Medical School/Harvar ...

and then moving with the group to

Rockefeller University The Rockefeller University is a Private university, private Medical research, biomedical Research university, research and graduate-only university in New York City, New York. It focuses primarily on the biological and medical sciences and pro ...

Academic career

Robbins joined the faculty at the

in 1960 as one of several young biochemists hired by

Jack Buchanan Walter John Buchanan (2 April 1890 – 20 October 1957) was a Scottish theatre and film actor, singer, dancer, producer and director. He was known for three decades as the embodiment of the debonair man-about-town in the tradition of George Gr ...

into the department of biology. There he worked particularly closely with

Salvador Luria Salvador Edward Luria (; ; born Salvatore Luria; August 13, 1912 – February 6, 1991) was an Italian microbiologist, later a Naturalized citizen of the United States#Naturalization, naturalized U.S. citizen. He won the Nobel Prize in Physiology ...

, studying the structure and biochemistry of

lipopolysaccharide Lipopolysaccharide (LPS), now more commonly known as endotoxin, is a collective term for components of the outermost membrane of the cell envelope of gram-negative bacteria, such as '' E. coli'' and ''Salmonella'' with a common structural archit ...

s. In 1998, after nearly 40 years at MIT, Robbins moved to the

School of Dental Medicine, where he has worked in collaboration with John Samuelson and with two of his own former postdoctoral fellows, department head Carlos Hirschberg and associate dean Maria Kukuruzinska. Robbins received the

Eli Lilly Award in Biological Chemistry The Eli Lilly Award in Biological Chemistry was established in 1934. Consisting of a bronze medal and honorarium, its purpose is to stimulate fundamental research in biological chemistry by scientists not over thirty-eight years of age. The Award i ...

in 1966, was elected to the

National Academy of Sciences The National Academy of Sciences (NAS) is a United States nonprofit, NGO, non-governmental organization. NAS is part of the National Academies of Sciences, Engineering, and Medicine, along with the National Academy of Engineering (NAE) and the ...

in 1982 and received the

Karl Meyer Karl Meyer may refer to: *Karl Meyer (activist) (born 1937), American pacifist, activist, Catholic worker and tax resister * Karl Meyer (aviator) (1894–1917), World War I flying ace *Karl Meyer (biochemist) (1899–1990), German biochemist * Karl ...

Award for Lifetime Achievement in Glycobiology in 2000.

Research

Robbins' research has focused on a variety of biochemical pathways. In his early career at MIT, he worked closely with Luria studying the structure and biosynthesis of

s, including elucidating the structure of bactoprenol and identifying the direction of chain elongation in LPS synthesis in bacteria. He later moved on to studying the biochemistry of the

eukaryotic The eukaryotes ( ) constitute the Domain (biology), domain of Eukaryota or Eukarya, organisms whose Cell (biology), cells have a membrane-bound cell nucleus, nucleus. All animals, plants, Fungus, fungi, seaweeds, and many unicellular organisms ...

N-linked glycosylation ''N''-linked glycosylation is the attachment of an oligosaccharide, a carbohydrate consisting of several sugar molecules, sometimes also referred to as glycan, to a nitrogen atom (the amide nitrogen of an asparagine (Asn) residue of a protein), i ...

pathway and more recently, with John Samuelson, has studied the evolution of this pathway in

protist A protist ( ) or protoctist is any eukaryotic organism that is not an animal, land plant, or fungus. Protists do not form a natural group, or clade, but are a paraphyletic grouping of all descendants of the last eukaryotic common ancest ...

s. He has also worked on the problem of

chitin Chitin (carbon, C8hydrogen, H13oxygen, O5nitrogen, N)n ( ) is a long-chain polymer of N-Acetylglucosamine, ''N''-acetylglucosamine, an amide derivative of glucose. Chitin is the second most abundant polysaccharide in nature (behind only cell ...

synthesis and its role in

yeast Yeasts are eukaryotic, single-celled microorganisms classified as members of the fungus kingdom (biology), kingdom. The first yeast originated hundreds of millions of years ago, and at least 1,500 species are currently recognized. They are est ...

References

{{DEFAULTSORT:Robbins, Phillips 1930 births Living people Boston University faculty American biochemists Members of the National Academy of Medicine